Navegando por Palavras-chave "Musa"

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    Os Benefícios Do Consumo De Biomassa De Banana Verde Em Pacientes Com Pré-Diabetes E Diabetes
    (Universidade Federal de São Paulo (UNIFESP), 2017-08-31) Costa, Edna Silva [UNIFESP]; Izar, Maria Cristina De Oliveira [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: Diabetes mellitus is a heterogeneous group of metabolic disorders, associated with microvascular complications, hyperglycemia, implying a higher risk of developing cardiovascular diseases. Intensive glycemic control (HbA1c ~ 7.0%) reduces chronic microvascular complications. The green banana presents significant levels of resistant starch, has physiological functions in intestinal regulation, glycemic control and delays gastric emptying. Objective: To evaluate the effects of green banana biomass consumption on patients with pre-diabetes (HbA1c between 5.7% and 6.4%) and diabetes (HbA1c≥6.5%) on anthropometric, biochemical and nutritional parameters. Methods: A total of 113 patients with a mean age of 65 years, followed for six months by means of periodic medical and nutritional care, were randomized between biomass group (n=62), who received specific nutritional orientation for the disease and consumed 40g of green banana biomass, approximately 4,5 g of resistant starch and control group (n=51), who received specific nutritional guidance for the disease. Clinical (blood pressure, anthropometric data, bioelectrical impedance) and laboratory parameters (fasting glycemia, HbA1c, total cholesterol and fractions, triglycerides, insulin) were evaluated at baseline and at the end of the study. Results: In the biomass group, a decrease in diastolic blood pressure (p=0.010), weight loss (p=0.002) and a consequent decrease in BMI (p=0.006) were observed. It was noted in both groups, decrease in waist circumference and hip circumference, respectively, in the biomass group (p<0.0001 and p=0.003) and in the control group (p<0.0001 and p=0.003). There was a significant decrease in fasting glycemia (p=0.021) and HbA1c (p=0.0001) in the biomass group, and a reduction in HbA1c (p=0.002) in the control group. There were no changes in total cholesterol, LDL-C, triglycerides in both groups, but a decrease in HDL-C in the control group (p=0.020) was observed. The percent variation of the biochemical parameters, between groups, presented statistical significance only for HDL-C (p=0.021). However, when the intervention was analyzed according to xxiii presence of diabetes or pre-diabetes, there was a trend in pre-diabetic patients to a greater reduction on glycemia (p=0.077) in the controls, and HbA1c (p=0.085) in those receiving green banana biomass, with no effect observed in patients with diabetes. After the follow-up checking the food consumption, in both groups we observed an increase in fiber consumption (biomass p<0.0001 and control p=0.020), decrease in lipid consumption in the diet (biomass p = 0.050 and control p=0.005) and polyunsaturated fat (biomass p<0.0001 and control p=0.014), there was an increase in cholesterol intake in the biomass group (p=0.018). In the control group, saturated fat intake was lower in the final period when compared to the biomass group (p=0.012). There was a decrease in the intake of these fats (p=0.020) and an increase in carbohydrate intake (p=0.009). Conclusion: Green banana biomass favorably modified the glucose metabolism and,anthropometry, being a good alimentary strategy, potentially improving metabolic control, especially in pre-diabetes.
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    Casca da Musa Sapientum Verde na cicatrização de ferida operatória em ratos
    (Universidade Federal de São Paulo (UNIFESP), 2010-08-25) Atzingen, Dênia Amélia Novato Castelli Von [UNIFESP]; Gragnani, Alfredo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: The use of unripe banana peel in wound care has been previously described, especially for oral administration. The indication for topical use requires further investigation. Objective: To evaluate the action of unripe banana (Musa sapientum) peel in the healing of surgical wounds in rats. Methods: The study was conducted with 120 rats, which were divided into two groups: the control group (gel without the active ingredient) and experimental group (4% unripe M. sapientum peel gel). The animals were anesthetized with ketamine and xylazine, a 4 x 4 cm surgical wound was created on the back of each animal, and the wound was covered with a primary dressing. The wounds were treated daily with 0.9% saline solution and the gel formulations were applied to their respective groups. The animals were euthanized on postoperative days 7, 14 and 21, and the tissue from the wound site with a margin of normal tissue was removed for histological analysis. Results: There were no significant differences between groups in mean wound contraction (p = 0.982). There were significant differences in the percentage of wound contraction between times of measurement within groups (p = 0.023). No significant differences were found between histological variables between groups. Only in the control group, there was a progressive increase with time in the number of collagen fibers (p = 0.035) and vascular proliferation (p = 0.033). In the experimental group, there were only significant differences in the number of polymorphonucleated cells between times of measurement (p = 0.026). Conclusion: The gel of unripe banana (M. sapientum) peel in the concentration of 4% did not improve the healing of surgical wounds in rats.