Navegando por Palavras-chave "HIV medication"

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    Predictors and Evolution of Antiretroviral Therapy Adherence Among Perinatally HIV-Infected Adolescents in Brazil
    (Elsevier Science Inc, 2016) Cote, Jose; Delmas, Philippe; de Menezes Succi, Regina Celia [UNIFESP]; Galano, Eliana; Auger, Patricia; Sylvain, Helene; Colson, Sebastien; Machado, Daisy Maria [UNIFESP]
    Purpose: Antiretroviral therapy medication adherence is a complex phenomenon influenced by multiple factors. This study examines its evolution and predictors among perinatally HIV-infected youths in Sao Paulo, Brazil. Methods: During a 1-year longitudinal cohort study, perinatally HIV-infected youths aged 13-21 years taking antiretroviral therapy were recruited in hospitals and HIV/AIDS reference centers. Data were collected at baseline and after 12 months. Variables assessed were adherence, self-efficacy regarding medication intake, social support, stress level, depression, CD4 cell count, viral load, and symptoms. Adherence was defined as taking >= 95% of prescribed HIV medication in the past 7 days. Generalized estimating equation and analysis of variance methods were used. Results: A total of 268 adolescents participated in the study (59% female