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- ItemAcesso aberto (Open Access)Efeitos do exercício na redução do risco de quedas em mulheres idosas com osteoporose(Universidade do Estado do Rio Janeiro, 2013-09-01) Teixeira, Lucas Emmanuel Pedro de Paiva; Peccin, Maria Stella [UNIFESP]; Silva, Kelson Nonato Gomes da [UNIFESP]; Oliveira, Aline Mizusaki Imoto de; Teixeira, Tiago José de Paiva; Costa, Joelma Magalhães da; Trevisani, Virgínia Fernandes Moça [UNIFESP]; Universidade Federal do Amazonas Departamento de Fisioterapia; Universidade Federal de São Paulo (UNIFESP); Hospital das Forças Armadas Serviço de Fisioterapia; Universidade Santo Amaro Residência em Reumatologia; Centro Universitário do Norte Departamento de FisioterapiaOBJECTIVE: This study aims to evaluate the effect of progressive muscular strength and proprioception training program on the balance and decrease in the risk of falls in women with osteoporosis. METHOD: 82 sedentary women aged 60-75 years with osteoporosis were selected and randomized in two groups: the intervention group comprised 41 patients submitted to an 18-week progressive muscular strength and proprioception training of quadriceps associated to drug therapy for osteoporosis; and control group, formed by 41 patients submitted to drug therapy only. The balance and fall risk were evaluated using the Balance Berg Scale (BBS) and calculating the Fall Index (FI). The number of fall was assessed six months before the research and the following six months. RESULTS: 69 patients completed the research. The program improved the functional balance (p<0.001) shown by BBS, decreased the risk of falls evidenced by the general score of FI (p<0.004) and also a decrease in the total number of falls. The experimental group showed significant lower number of falls when compared to the control group (p<0.001). CONCLUSION: The association of progressive strength of quadriceps and proprioceptive training is effective to prevent falls and reduce risk factors. The quantitative model to predict risk of falls might be useful to identify the risk of falls in the elderly. Trial registration: 082213-ANZCTR.
- ItemSomente MetadadadosEstimulação Elétrica Nervosa Transcutânea E Fotobiomodulação Associado Ao Exercício Terapêutico Na Dor E Qualidade De Vida Da Osteoartrite De Joelho: Revisão Sistemática Com Metanálise(Universidade Federal de São Paulo (UNIFESP), 2018-04-16) Silva, Fabio Leite [UNIFESP]; Pinfildi, Carlos Eduardo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Background: Osteoarthritis Can Be Considered As A Chronic Disease With Several Disturbs Characterized By Joint Cartilage Degeneration With Slow Progression Associated To Painful Symptoms. Several Electrophysical Agents (Epas) Have Been Studied Associated To Therapeutic Exercises To Improve Pain And Quality Of Life. The Most Epas Studied Are Photobiomodulation (Pbm) And Transcutaneous Electrical Nerve Stimulation (Tens). Objective: To Compare The Effectiveness Of Pbm And Tens Associated To Therapeutic Exercises In Quality Of Life And Pain In Patients With Knee Osteoarthritis. Method: A Systematic Review Of The Randomized Clinical Trial (Rct) Was Performed Following The "Preferred Reporting Itens For Systematic Reviews" (Prisma) Criteria Aged From January 1st, 1980 To March 31st, 2018. Al The Eligibility Criteria Were Performed By Two Reviewers With The Purpose To Evaluate The Risks And Bias. Results: At The First Search, 6.613 Studies Related To Pbm And 8.739 Related To Tens Were Found. After The Second Screen
- ItemAcesso aberto (Open Access)Treinamento aeróbico n-acetilcisteina na modulação do receptor P2X7 e na progressão da nefropatia diabética experimental(Universidade Federal de São Paulo (UNIFESP), 2013) Rodrigues, Adelson Marçal [UNIFESP]; Higa, Elisa Mieko Suemitsu [UNIFESP]; http://lattes.cnpq.br/8578252701813423; http://lattes.cnpq.br/0707094744828033Estudos em nosso Laboratorio com suplementacao de N-acetilcisteina (NAC) ou treinamento aerobico mostraram-se ferramentas eficazes contra o estresse oxidativo, atenuando a progressao da nefropatia diabetica em ratos. Receptores P2X7 (P2X7-R) em condicoes patologicas estao significantemente auto expressos em todo o organismo e aumentam os niveis de estresse oxidativo. O estudo visa avaliar a influencia do treinamento aerobico, da NAC e do P2X7-R e no desenvolvimento da nefropatia diabetica. Ratos Wistar machos foram todos nefrectomizados unilateralmente e o diabetes mellitus foi induzido usando estreptozotocina (60mg/kg, i.v.). O treinamento aerobico foi feito sobre esteira com taxa de trabalho de 16m/minuto por 60 minutos por dia, 5 dias por semana durante 8 semanas (CTL+EX e DM+EX); os ratos sedentarios foram mantidos em repouso sobre a esteira desativada (CTL+SE e DM+SE). Metade dos animais de cada grupo foi tratada com NAC (600mg/L) (CTL+SE+NAC, CTL+EX+NAC, DM+SE+NAC e DM+EX+NAC) e os outros receberam agua (n=10 para todos os grupos). Resultados foram descritos como medias ±EP; com significancia para p<0,05. DM+SE quando comparado a CTL+SE piora o perfil metabolico e a funcao renal, ainda houve aumento significante do estresse oxidativo, reducao da razao entre as glutationas (GSR/GPx) e da biodisponibilidade do oxido nitrico (NOo); viu-se ainda que a expressao dos P2X7-R estava significantemente elevada (43,25 ±5,45% vs 0,59 ±0,06%), juntamente com a mobilidade de calcio via BzATP (1,0 ±0,23 vs 0,14±0,06) ou ATP (0,38 ±0,16 vs 0,034 ±0,01). No entanto, todas as alteracoes do perfil metabolico e disfuncionalidade renal foram atenuadas com os tratamentos com NAC ou exercicios, principalmente quando ambos eram dados simultaneamente; ainda reduziu-se a expressao e a ativacao do P2X7-R via BzATP ou ATP, seja pela suplementacao de NAC (34,87 ±4,34%; 0,27 ±0,06; 0,20 ±0,04; respectivamente), pelo treinamento aerobico (25,60 ±3,44%; 0,31 ±0,08; 0,21 ±0,03; respectivamente) ou ambos (3,85 ±0,56%; 0,17 ±0,04; 0,14 ±0,01; respectivamente). Baseados em nossos achados, vimos a possibilidade da ativacao do P2X7-R poder ser parcialmente dependente do estresse oxidativo, onde poderia haver um mecanismo intracelular de inibicao pelo NOo sobre 0 receptor via nitrosilacao da extremidade C-terminal. Sugerimos que a busca da homeostase redox feita por tratamentos alternativos como a NAC e treinamento aerobico ou o uso de inibidores para o P2X7-R poderia ser util no retardamento da nefropatia diabetica, contudo mais estudos seriam necessarios para confirmar estes nossos achados
- ItemAcesso aberto (Open Access)Treinamento resistido progressivo nas doenças musculoesqueléticas crônicas(Sociedade Brasileira de Reumatologia, 2009-12-01) Jorge, Renata Trajano [UNIFESP]; Souza, Marcelo Cardoso de [UNIFESP]; Jones, Anamaria [UNIFESP]; Lombardi Júnior, Imperio [UNIFESP]; Jennings, Fábio [UNIFESP]; Natour, Jamil [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)INTRODUCTION: Progressive resistance training has been suggested as a therapeutic modality that attempts to promote the standardization of the prescription of physical exercises in physical therapy, besides optimizing the results of the treatment. OBJECTIVE: To review studies that used progressive resistance training in chronic musculoskeletal diseases and to demonstrate the importance of including this type of training in the rehabilitation of those diseases. SOURCE OF THE DATA: Pubmed, Medline, and Lilacs databases were reviewed without restrictions of date and/or language. REVIEW: Due to the countless benefits attributed to this treatment modality, the importance of exercises in physical therapy has been well documented. Despite the proven efficacy, high-intensity exercises are not routinely prescribed, and this prescription is usually not standardized, which does not allow a consensus on the type of strengthening used, as well as load calculation and progression. Progressive resistance training implies the gradual increase in load during the training period. The number of repetitions that each individual can complete depends on the calculation of the maximal repetition. CONCLUSION: Based on the findings of this review, the use of progressive resistance training to complement traditional exercises used in rehabilitation of chronic musculoskeletal diseases is recommended in order to standardize treatment protocols, with adequate control of individual load, and to optimize training results. However, it should be emphasized that further studies are necessary for more reliable conclusions.