Navegando por Palavras-chave "Cobalt radioisotopes"

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    Alterações hematológicas em camundongos da raça C57BL expostos a irradiação corpo inteiro pelo cobalto radioativo (60Co)
    (Universidade Federal de São Paulo (UNIFESP), 1984) Segreto, Roberto Araujo [UNIFESP]
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    Single institutional retrospective analysis: treatment of choroidal melanomas with cobalt-60 brachytherapy
    (Conselho Brasileiro de Oftalmologia, 2004-06-01) Pellizzon, Antônio Cássio Assis; Salvajoli, João Victor; Novaes, Paulo Eduardo; Fogaroli, Ricardo; Ferrigno, Robson; Maia, Maria Aparecida Conte; Chojniak, Marta Motono; Erwene, Clélia Maria [UNIFESP]; Hospital do Câncer - AC Camargo Centro de Tratamento Pesquisa Department of Radiation Oncology; Instituto Arnaldo Vieira de Carvalho; Hospital do Câncer - AC Camargo Centro de Tratamento Pesquisa Department of Onco-opthalmology; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: To evaluate the outcome of patients with choroidal melanoma treated with conservative therapy with brachytherapy (episcleral Co-60 plaque therapy) at the Hospital do Cancer São Paulo, Brazil. METHODS: We evaluated 102 patients consecutively treated from January, 1999 to June, 1999. Median age, maximum tumor base diameter and apex size were 55.5 years, 9.75 mm and 5 mm, respectively. Doses at the base of the tumor, including 1 mm of sclera, ranged from 157 to 487 Gy (median 284.5 Gy) and to the apex from 37 to 220 Gy (median 106 Gy). RESULTS: The crude eye preservation rate with conservative therapy alone was 78.5%. Five-year overall actuarial survival rate was 92.2% and eye conservation rate was 78%. Side effects were mostly an uncomplicated retinopathy in 39/102 patients (38.2%); macular degeneration or scarring led to poor central vision in 31/102 patients (30.3%) of cases. CONCLUSION: Our experience with cobalt-60 plaque brachytherapy achieved a satisfactory rate of local tumor control, despite the oversized base diameters of treated tumors.