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Title: Outcomes in orthopedics and traumatology: translating research into practice
Authors: Moraes, Vinícius Ynoe de [UNIFESP]
Ferrari, Paula Martins de Oliveira
Gracitelli, Guilherme Conforto
Faloppa, Flávio [UNIFESP]
Belloti, Joao Carlos [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: Orthopedics
Knee joint
Platelet-rich plasma
Evidence-based medicine
Outcomes research
Issue Date: 1-Dec-2014
Publisher: Sociedade Brasileira de Ortopedia e Traumatologia
Citation: Acta Ortopédica Brasileira. Sociedade Brasileira de Ortopedia e Traumatologia, v. 22, n. 6, p. 330-333, 2014.
Abstract: Clinical research is focused in generating evidence that is feasible to be applicable to practitioners. However, translating research-focused evidence into practice may be challenging and often misleading. This article aims is to pinpoint these challenges and suggest some methodological safeguards, taking platelet-rich plasma therapies and knee osteochondral injuries as examples. Studies and systematic reviews involving the following concepts will be investigated: clinically relevant outcomes, systematic errors on sample calculation, internal and external validity. Relevant studies on platelet-rich plasma for muscle-tendon lesions and updates on osteochondral lesions treatment were included in this analysis. Authors and clinicians should consider these concepts for the implementation and application of dissemination of the best evidence. Research results should be challenged by a weighted analysis of its methodological soundness and applicability. Level of Evidence V, Therapeutic Studies - Investigating the Results of Treatment.
ISSN: 1413-7852
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