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https://repositorio.unifesp.br/handle/11600/6270| Title: | Clinical and microbiological characterization of KPC-producing Klebsiella pneumoniae infections in Brazil |
| Authors: | Beirão, Elisa Maria Furtado, Juvencio Jose Duailibe Girardello, Raquel [UNIFESP] Ferreira Filho, Heli Gales, Ana Cristina [UNIFESP] Hospital Heliópolis Hospital Heliópolis Department of Infectious Diseases Universidade Federal de São Paulo (UNIFESP) Hospital Heliópolis Microbiology Laboratory |
| Keywords: | Klebsiella pneumonia KPC hospital infection carbapenemase |
| Issue Date: | 1-Feb-2011 |
| Publisher: | Brazilian Society of Infectious Diseases |
| Citation: | Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 15, n. 1, p. 69-73, 2011. |
| Abstract: | In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center. |
| URI: | http://repositorio.unifesp.br/handle/11600/6270 |
| ISSN: | 1413-8670 |
| Other Identifiers: | http://dx.doi.org/10.1590/S1413-86702011000100013 |
| Appears in Collections: | Artigo |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| S1413-86702011000100013.pdf | 767.04 kB | Adobe PDF | View/Open |
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