Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/5698
Title: Clinical and microbiological characteristics of bloodstream infections in a tertiary hospital in Maceió, Alagoas, Brazil
Authors: Tenório, Maria Tereza Freitas [UNIFESP]
Porfírio, Zenaldo [UNIFESP]
Lopes, Antonio Carlos [UNIFESP]
Cendon Filha, Sônia Perez [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Universidade de Ciências da Saúde de Alagoas
Keywords: bloodstream infections
blood cultures
bacteremia
spesis
Issue Date: 1-Apr-2010
Publisher: Brazilian Society of Infectious Diseases
Citation: Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 14, n. 2, p. 175-179, 2010.
Abstract: We observed the clinical and microbiological characteristics of several stages of bloodstream infections (BSI), as well as the mortality attributed to it in a tertiary hospital in the northeast of Brazil (in the city of Maceió, Alagoas). A prospective cohort of 143 patients who had at least one positive blood culture was enrolled in the study. Their clinical evolution was followed up for 30 days from October 2005 to December 2006. The relation among the qualitative variables was verified through Chi-square test. The significance level was 5%. The statistical package adopted was SPSS 15.0 for Windows. Up to the thirtieth day, 30.1% of the patients presented bacteremia and 69.9% developed sepsis.Among these, 20.3% developed severe sepsis and 10.5% septic shock. The mortality attributed to it was 37.8%. In bacteremia, sepsis, severe sepsis, and septic shock conditions, mortality rates were 9.3%, 50%, 65.5%, and 84.6%, respectively. Respiratory (32.2%) and urinary (14%) sources and the ones related to central venous catheter (14%) were prevalent. In the wards 55.12% of the cases developed sepsis, whereas in the intensive care units, the rate was 87.69% (p < 0.05). Chronic renal failure, diabetes melitus, and neuropathy were present in 21.7%, 26.6%, and 29.4% of the cases, respectively. Coagulase-negative Staphylococcus (25.9%), Staphylococcus aureus (21%), and Klebsiella pneumoniae (14%) were the most present microorganism in the sample. The high morbidity and mortality rates in this study are attributed to the lack of knowledge on BSI characteristics and on instituted protocols for detection and treatment in early stages.
URI: http://repositorio.unifesp.br/handle/11600/5698
ISSN: 1413-8670
Other Identifiers: http://dx.doi.org/10.1590/S1413-86702010000200011
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