Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/56613
Title: Neuropsychiatric Lupus in clinical practice
Authors: Alessi, Helena [UNIFESP]
Dutra, Livia Almeida [UNIFESP]
Braga-Neto, Pedro
Pedroso, Jose Luiz [UNIFESP]
Toso, Fabio Fieni [UNIFESP]
Kayser, Cristiane [UNIFESP]
Barsottini, Orlando Graziani Povoas [UNIFESP]
Keywords: systemic lupus erythematosus
lupus vasculitis
central nervous system
seizures
myelitis
autoimmune diseases
Issue Date: 2016
Publisher: Assoc Arquivos Neuro- Psiquiatria
Citation: Arquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 12, p. 1021-1030, 2016.
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations. This article reviews major neuropsychiatric manifestations in patients with SLE and discusses their clinical features, radiological findings and treatment options.
URI: https://repositorio.unifesp.br/handle/11600/56613
ISSN: 0004-282X
Other Identifiers: http://dx.doi.org/10.1590/0004-282X20160150
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