Please use this identifier to cite or link to this item:
|Title:||Toward Quantitative Optical Coherence Tomography Angiography Visualizing Blood Flow Speeds in Ocular Pathology Using Variable Interscan Time Analysis|
|Authors:||Ploner, Stefan B.|
Moult, Eric M.
Waheed, Nadia K.
Novais, Eduardo Amorim [UNIFESP]
Cole, Emily D.
Rosenfeld, Philip J.
Duker, Jay S.
Fujimoto, James G.
|Keywords:||ocular blood flow|
variable interscan time analysis (VISTA)
optical coherence tomography (OCT)
optical coherence tomography angiography (OCTA)
age-related macular degeneration
nascent geographic atrophy
|Publisher:||Lippincott Williams & Wilkins|
|Citation:||Retina-The Journal Of Retinal And Vitreous Diseases. Philadelphia, v. 36, n. 12, p. S118-S126, 2016.|
|Abstract:||Purpose: Currently available optical coherence tomography angiography systems provide information about blood flux but only limited information about blood flow speed. The authors develop a method for mapping the previously proposed variable interscan time analysis (VISTA) algorithm into a color display that encodes relative blood flow speed. Methods: Optical coherence tomography angiography was performed with a 1,050 nm, 400 kHz A-scan rate, swept source optical coherence tomography system using a 5 repeated B-scan protocol. Variable interscan time analysis was used to compute the optical coherence tomography angiography signal from B-scan pairs having 1.5 millisecond and 3.0 milliseconds interscan times. The resulting VISTA data were then mapped to a color space for display. Results: The authors evaluated the VISTA visualization algorithm in normal eyes (n = 2), nonproliferative diabetic retinopathy eyes (n = 6), proliferative diabetic retinopathy eyes (n = 3), geographic atrophy eyes (n = 4), and exudative age-related macular degeneration eyes (n = 2). All eyes showed blood flow speed variations, and all eyes with pathology showed abnormal blood flow speeds compared with controls. Conclusion: The authors developed a novel method for mapping VISTA into a color display, allowing visualization of relative blood flow speeds. The method was found useful, in a small case series, for visualizing blood flow speeds in a variety of ocular diseases and serves as a step toward quantitative optical coherence tomography angiography.|
|Appears in Collections:||Artigo|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.