Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/55261
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLima, Luiz H. [UNIFESP]
dc.contributor.authorde Andrade, Gabriel Costa [UNIFESP]
dc.contributor.authorVianello, Silvana [UNIFESP]
dc.contributor.authorZett, Claudio [UNIFESP]
dc.contributor.authorFarah, Michel E. [UNIFESP]
dc.contributor.authorBelfort, Rubens, Jr. [UNIFESP]
dc.date.accessioned2020-07-17T14:03:15Z-
dc.date.available2020-07-17T14:03:15Z-
dc.date.issued2017
dc.identifierhttp://dx.doi.org/10.1186/s12348-016-0119-7
dc.identifier.citationJournal Of Ophthalmic Inflammation And Infection. Heidelberg, v. 7, p. -, 2017.
dc.identifier.issn1869-5760
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/55261-
dc.description.abstractBackground: Retrospective review of one acute syphilitic posterior placoid chorioretinitis (ASPPC) case with serological evidence of syphilis who had ocular signs and symptoms not attributable to other diseases. Enface and spectral-domain optical coherence tomographySD-OCT were analyzed at the time of presentation and at 1-month visit following initiation of treatment. The study patient underwent standard treatment for neurosyphilis. Results: Ophthalmic examination and imaging studies were consistent with the diagnosis of ASPPC. The patient age was 33 year-old and the baseline visual acuity was 20/400 and 20/80 in the right and left eyes, respectively. At presentation, SD-OCT scans showed disruption and loss of the ellipsoid zone (EZ), small nodular elevations on retinal pigment epithelium (RPE) and punctate hyperreflectivity in the choroid. Enface OCT at the level of RPE and EZ demonstrated multiple hyperreflective dot-like lesions simmetrically distributed within the macular area. These dot-like lesions corresponded to the small nodular elevations on RPE and to disruption/loss of EZ observed with SD-OCT. One month after neurosyphilis therapy, the visual acuity improved and the outer retinal changes partially reversed in both eyes. Conclusions: We report the outer retinal findings and its correlation using both en-face and SD-OCT in a patient with ASPPC. En-face OCT imaging provides a more precise outer retinal layers analyses allowing a better understanding of the ASPPC pathophysiology.en
dc.format.extent-
dc.language.isoeng
dc.publisherSpringer Heidelberg
dc.relation.ispartofJournal Of Ophthalmic Inflammation And Infection
dc.rightsAcesso aberto
dc.subjectAcute syphilitic posterior placoid chorioretinitisen
dc.subjectEn-face optical coherence tomographyen
dc.subjectSpectral-domain optical coherence tomographyen
dc.subjectSyphilisen
dc.subjectOuter retinal abnormalitiesen
dc.titleMultimodal imaging analyses of hyperreflective dot-like lesions in acute syphilitic posterior placoid chorioretinopathyen
dc.typeArtigo
dc.description.affiliationUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationFed Univ Sao Paulo UNIFESP, Rua Botucatu,821,Vila Clementino, BR-04023062 Sao Paulo, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ophthalmol, Sao Paulo, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP, Rua Botucatu,821,Vila Clementino, BR-04023062 Sao Paulo, SP, Brazil
dc.identifier.fileWOS000391764400001.pdf
dc.identifier.doi10.1186/s12348-016-0119-7
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000391764400001
dc.coverageHeidelberg
dc.citation.volume7
Appears in Collections:Artigo

Files in This Item:
File SizeFormat 
WOS000391764400001.pdf1.1 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.