Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/54047
Title: Assessing risk of bias in randomized controlled trials of methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
Authors: Rodrigues-Tartari, Raissa [UNIFESP]
Swardfager, Walter
Salum, Giovanni A.
Rohde, Luis A.
Cogo-Moreira, Hugo [UNIFESP]
Keywords: ADHD
confirmatory factor analysis
meta-analysis
methylphenidate
risk of bias
Issue Date: 2018
Publisher: Wiley
Citation: International Journal Of Methods In Psychiatric Research. Hoboken, v. 27, n. 1, p. -, 2018.
Abstract: To test how reliable the tool recommend by Cochrane Collaboration for assessing risk of bias systematic reviews of randomized clinical trials is in the context of methylphenidate for children and adolescents with attention deficit hyperactivity disorder. Confirmatory factor analysis was used to evaluate a unidimensional model for the 7 indicators, applied to 184 Randomized Clinical Trial (RCTs) within a 2015 Cochrane systematic review titled Methylphenidate for children and adolescents with attention deficit hyperactivity disorder. A unidimensional model resulted in excellent adequacy indices, but only 2 indicators had very high factor loadings and low measurement errors. In terms of content, the 7 indicators showed poor reliability (=0.642)
however, the set of indicators was precise in evaluating studies with a high amount of bias risk. The Cochrane model of risk of bias as it is, exhibited good fit indices but the majority of the items were not reliable to adequately capture risk of bias in the context of clinical trials of methylphenidate for ADHD.
URI: https://repositorio.unifesp.br/handle/11600/54047
ISSN: 1049-8931
Other Identifiers: http://doi.org/10.1002/mpr.1586
Appears in Collections:Artigo

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.