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dc.contributor.authorVale, Thiago Cardoso
dc.contributor.authorFernandes do Prado, Lucila Bizari [UNIFESP]
dc.contributor.authordo Prado, Gilmar Fernandes [UNIFESP]
dc.contributor.authorPovoas Barsottini, Orlando Graziani [UNIFESP]
dc.contributor.authorPedroso, Jose Luiz [UNIFESP]
dc.identifier.citationSleep. Westchester, v. 39, n. 1, p. 117-120, 2016.
dc.description.abstractStudy Objectives: To report two female patients with paraneoplastic cerebellar degeneration (PCD) related to breast cancer that presented with rapid eye movement-sleep behavior disorder (RBD) and improved sleep symptoms with immunotherapy. Methods: The two patients were evaluated through clinical scale and polysomnography before and after therapy with intravenous immunoglobulin. Results: RBD was successfully treated with immunotherapy in both patients. Score on the RBD screening questionnaire dropped from 10 to 1 or 0, allied with the normalization of polysomnographic findings. Conclusions: A marked improvement in RBD after immunotherapy in PCD raises the hypothesis that secondary RBD may be an immune-mediated sleep disorder.en
dc.publisherAmer Acad Sleep Medicine
dc.rightsAcesso aberto
dc.subjectparaneoplastic cerebellar degenerationen
dc.subjectREM sleepen
dc.subjectREM-sleep behavior disorderRem-Sleepen
dc.subjectLimbic Encephalitisen
dc.titleRapid Eye Movement Sleep Behavior Disorder in Paraneoplastic Cerebellar Degeneration: Improvement with Immunotherapyen
dc.description.affiliationFed Univ Juiz de Fora UFJF, Fac Med, Dept Internal Med, Movement Disorders Unit,Neurol Serv,Univ Hosp, Juiz De Fora, MG, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurol, Div Gen Neurol, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Neurol, Ataxia Unit, Sao Paulo, Brazil
dc.description.affiliationUnifespDivision of General Neurology and Ataxia Unit, Department of Neurology, Universidade Federal São Paulo, São Paulo, Brazil
dc.description.sourceWeb of Science
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