Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/49636
Title: Risk factors for recurrent wheezing - international study of wheezing in infants (eisl) phase 3
Authors: Aranda, Carolina Sanchez [UNIFESP]
Wandalsen, Gustavo Falbo [UNIFESP]
Fonzar, Ligia Furtado [UNIFESP]
Dela Bianca, Ana Caroline Cavalcanti
Mallol, Javier
Solé, Dirceu [UNIFESP]
Keywords: Asthma
Infants
Respiratory Sounds
Respiratory Tract Infections
Risk Factors1st Year
Childhood Asthma
Life
Prevalence
Infections
Exposure
Questionnaire
Acetaminophen
Validation
Disorders
Issue Date: 2016
Publisher: Elsevier doyma sl
Citation: Allergologia Et Immunopathologia. Barcelona, v. 44, n. 1, p. 3-8, 2016.
Abstract: Background: We aimed to identify factors associated with recurrent wheezing (RW) in infants in the first year of life living in the Southern region of Sao Paulo city and participating in the "Estudio Internacional de Sibilancias en Lactantes (EISL)" - phase 3 (P3). Methods: 1335 parents of infants who were attended in primary care health units in the Southern region of Sao Paulo city from 2009 to 2010 answered the EISL-P3 written questionnaire. The wheezing group was stratified in accordance to the frequency of wheezing episodes as occasional wheezing (OW, less than three episodes), or RW (three or more episodes). Wheezing-associated factors were evaluated using multivariate analysis and were expressed as odds ratio (OR) and 95% confidence interval (95%CI). Results: The most relevant factors related to OW were pneumonia (OR = 3.10, 95%CI=1.68-5.73), hospitalisation due to pneumonia (OR = 2.88, 95%CI = 1.26-6.56) and recurrent upper respiratory infection (URI, OR = 1.87, 95%CI = 1.25-2.81). Regarding RW, recurrent URI (OR = 5.34, 95%CI = 3.83-7.45), pneumonia (OR= 4.06, 95%CI = 2.87-5.74) and asthmatic siblings (OR= 3.02, 95%CI = 1.67-5.45) were the most significantly associated factors. Conclusions: In the present study, we found that recurrent URI, positive history of pneumonia and familiar history of asthma were the most relevant factors associated with RW. The precocious knowledge of these factors can enable the identification of the probable asthmatic infants and can improve both prevention strategies and treatment of these patients. (C) 2014 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.
URI: http://repositorio.unifesp.br/handle/11600/49636
ISSN: 0301-0546
Other Identifiers: http://dx.doi.org/10.1016/j.aller.2015.05.011
Appears in Collections:Artigo

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