Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/4736
Full metadata record
DC FieldValueLanguage
dc.contributor.authorVaidergorn, Jairo [UNIFESP]
dc.contributor.authorFagundes, Djalma José [UNIFESP]
dc.contributor.authorMachado, Ana Lucia
dc.contributor.authorFerreira, Rimarcs Gomes [UNIFESP]
dc.contributor.authorJuliano, Yara
dc.contributor.authorNovo, Neil Ferreira [UNIFESP]
dc.contributor.authorGomes, Paulo de Oliveira [UNIFESP]
dc.date.accessioned2015-06-14T13:38:55Z
dc.date.available2015-06-14T13:38:55Z
dc.date.issued2008-12-01
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502008000600005
dc.identifier.citationActa Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 23, n. 6, p. 497-500, 2008.
dc.identifier.issn0102-8650
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/4736
dc.description.abstractPURPOSE: To create an animal model of extensive longitudinal tracheal stenosis (TS) that can be useful to test different surgical techniques of tracheal reconstruction. METHODS: Twenty male mongrel dogs were submitted to standard TS and randomly distributed to observation for 3 weeks (n=10) or 6 weeks (n=10). Under general anesthesia, an elliptical area (major axis from 1st to 20th ring and minor axis 40% of tracheal diameter) was resected and the stumps were sutured. The internal and external diameters were measured (before and after the observation time) and the stenosis index was calculated. Blood samples were collected (gasometry, hematocrit and hemoglobin.) before and after the surgical proceedings. RESULTS: The weight was significant lower in the animals of 6 weeks (15,551±3286.2) in comparison with those of 3 weeks observation (17,250±3575.0). No significant differences were noted in the extension of the trachea on the 21st day (21.2± 1.8) or 42nd day (21.1±1.7). The mean (40.1) and the median (40.5) of rings counted on the 21st day were quite similar to mean (38.1) and median (39.0) that were counted on the 42nd day. In the animals of group A (3 weeks) the mean (46.8%) and the median (49.8%) of index stenosis showed no significant difference (Mann Whitney test p<0.001) in comparison with the mean (55.1%) and median (52.4%) of the animals from group B (6 weeks). No mechanical or biochemical distresses were recorded through all period of observation. CONCLUSION: The surgical proceeding was effective to promote a model of longitudinal and extensive tracheal stenosis.en
dc.description.abstractOBJETIVO: Criar um modelo de estenose longitudinal extensa que possa ser útil para testar diferentes técnicas operatórias de reconstrução traqueal. MÉTODOS: 20 cães sem raça definida foram submetidos a um procedimento padrão de estenose traqueal extensa e observados por três (n=10) ou seis (n=10) semanas. Sob anestesia geral uma área elíptica (eixo maior do 1º ao 20º anel traqueal e eixo menos com 40% do diâmetro da luz traqueal) foi ressecada e os cotos foram anastomosados de modo término-terminal. O diâmetro interno e externo foi medido (antes e depois do período de observação) e o índice de estenose foi determinado. Amostras de sangue foram coletadas (gasometria, hematócrito e hemoglobina) antes e depois dos procedimentos operatórios. RESULTADOS: O peso foi significantemente menor nos animais de seis semanas (15,551±3286.2) em comparação com os de três semanas (17,250±3575.0). Não houve diferenças significantes entre a extensão da traquéia com três (21.2± 1.8) ou seis (21.1±1.7) semanas. A média (40.1) e a mediana (40.5) dos anéis contados na 3ª semana foi similar à média (38.1) e mediana (39.0 da 6ª semana. A média (46.8%) e mediana (49.8%) do índice de estenose com três semanas não mostrou diferenças significantes (Mann Whitney test p<0.001) com a média 55.1%) e mediana de seis semanas (52.4%). Nenhum sofrimento mecânico ou bioquímico da respiração foi assinalado. CONCLUSÃO: O procedimento foi efetivo para promover um modelo de estenose extensa da traquéia.pt
dc.format.extent497-500
dc.language.isoeng
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartofActa Cirurgica Brasileira
dc.rightsAcesso aberto
dc.subjectTracheal Stenosisen
dc.subjectModels, Animalen
dc.subjectDogsen
dc.subjectEstenose Traquealpt
dc.subjectModelos Animaispt
dc.subjectCãespt
dc.titleModel of extensive and severe tracheal stenosis in dogsen
dc.title.alternativeModelo de estenose traqueal extensa e grave em cãespt
dc.typeArtigo
dc.contributor.institutionSanto Amaro University Medicine School Cardio-Thoracic Surgery Division
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUNISA Medicine School
dc.contributor.institutionUNISA Medicine School Pathological Anatomy Division
dc.description.affiliationSanto Amaro University Medicine School Cardio-Thoracic Surgery Division
dc.description.affiliationFederal University of São Paulo Department of Surgery Operative Technique and Experimental Surgery Division
dc.description.affiliationUNISA Medicine School
dc.description.affiliationUNISA Medicine School Pathological Anatomy Division
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Department of Surgery
dc.description.affiliationUnifespUNIFESP, Department of Surgery Operative Technique and Experimental Surgery Division
dc.description.affiliationUnifespUNIFESP, Department of Surgery
dc.identifier.fileS0102-86502008000600005.pdf
dc.identifier.scieloS0102-86502008000600005
dc.identifier.doi10.1590/S0102-86502008000600005
dc.description.sourceSciELO
dc.identifier.wosWOS:000264560100005
Appears in Collections:Artigo

Files in This Item:
File Description SizeFormat 
S0102-86502008000600005.pdf135.15 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.