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Title: Jack bean seed coat contains a protein with complete sequence homology to bovine insulin
Authors: Oliveira, Antonia Elenir Amancio
Machado, Olga Lima Tavares
Gomes, Valdirene Moreira [UNIFESP]
Xavier-Neto, José
Pereira, Alexandre Costa
Vieira, JGH
Fernandes, Katia Valeski Sales
Xavier Filho, Jose
Univ Estadual Norte Fluminense
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Secoes Endocrinol & Desenvolvimento Tecnico
Issue Date: 1-Feb-1999
Publisher: Bentham Science Publ Bv
Citation: Protein And Peptide Letters. Hilversum: Bentham Science Publ Bv, v. 6, n. 1, p. 15-21, 1999.
Abstract: The present study reports that a protein with complete sequence homology to bovine insulin is present in Jack bean (Canavalia ensiformis) seed coals. This protein was recognized by anti-human insulin antibodies and lowered blood glucose levels of alloxanized mice, indicating that it possesses biological potency. Our results suggest that insulin-like activities previously found in diverse plant tissues may be indeed due to insulin and indicate that insulin-dependent signaling pathways have been remarkably conserved during evolution.
ISSN: 0929-8665
Appears in Collections:Artigo

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