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Title: Treatment of Resistant Obsessive-Compulsive Disorder With Ventral Capsular/Ventral Striatal Gamma Capsulotomy: A Pilot Prospective Study
Authors: Lopes, Antonio Carlos
Greenberg, Benjamin D.
Noren, Georg
Canteras, Miguel Montes
Busatto, Geraldo F.
Mathis, Maria Eugenia de
Taub, Anita
D'Alcante, Carina Chaubet
Hoexter, Marcelo Queiroz [UNIFESP]
Gouvea, Fernando Sauerbronn
Cecconi, Janaina Philippi
Gentil, Andre F.
Ferrao, Ygor Arzeno
Fuentes, Daniel
Castro, Claudio Campi de
Leite, Claudia C.
Salvajoli, Joao Victor
Duran, Fabio L. S.
Rasmussen, Steven
Miguel, Euripedes Constantino
Universidade de São Paulo (USP)
Brown Univ
Hosp Santa Paulo
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 1-Sep-2009
Publisher: Amer Psychiatric Publishing, Inc
Citation: Journal Of Neuropsychiatry And Clinical Neurosciences. Arlington: Amer Psychiatric Publishing, Inc, v. 21, n. 4, p. 381-392, 2009.
Abstract: A subgroup of obsessive-compulsive disorder (OCD) patients remains refractory to conventional treatments. For them, a new stereotactic radiosurgery has been recently developed: the ventral capsular/ventral striatal (VC/VS) gamma capsulotomy. The authors aim to report efficacy and adverse events of VC/VS gamma capsulotomy. Five refractory OCD patients were selected. The authors assessed OCD, anxiety and depressive symptoms, and side effects pre- and postoperatively. Three patients (60%) met response criteria 48 months after surgery. Adverse effects were episodic and transient. Ventral capsular/ventral striatal gamma capsulotomy holds therapeutic promise, with few adverse effects. (The Journal of Neuropsychiatry and Clinical Neurosciences 2009; 21:381-392)
ISSN: 0895-0172
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Appears in Collections:Artigo

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