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|Title:||Antimicrobial susceptibility profile of contemporary clinical strains of Stenotrophomonas maltophilia isolates: Can moxifloxacin activity be predicted by levofloxacin MIC results?|
|Authors:||Gales, Ana Cristina [UNIFESP]|
Jones, R. N.
Sader, Helio Silva [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
in vitro activity
|Citation:||Journal Of Chemotherapy. Florence: Esift Srl, v. 20, n. 1, p. 38-42, 2008.|
|Abstract:||The susceptibility profile of 763 Stenotrophomonas maltophilia isolates was evaluated against 16 antimicrobials by the CLSI reference broth microdilution method. Minocycline (MIC90, 1 mu g/ml; 100.0% susceptible) was the most active compound, followed by doxycycline (MIC90, 4 mu g/ml; 99.6% susceptible), trimethoprim/sulfamethoxazole (MIC90, 1 mu g/ml; 97.8% susceptible), and tigecycline (MIC 90, 2 mu g/ml). An excellent correlation between levofloxacin (MIC90, 4 mu g/ml; 86.5% susceptible by published breakpoint criteria) and moxifloxacin (MIC90, 2 mu g/ml) MIC results was observed indicating that moxifloxacin could be further evaluated as a therapeutic option for S. maltophilia infections.|
|Appears in Collections:||Artigo|
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