Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/43728
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPayão, Spencer Luiz Marques [UNIFESP]
dc.contributor.authorSmith, MDC
dc.contributor.authorKormann-Bortolotto, Maria Helena [UNIFESP]
dc.contributor.authorToniolo Neto, João [UNIFESP]
dc.date.accessioned2018-06-15T17:30:21Z-
dc.date.available2018-06-15T17:30:21Z-
dc.date.issued1994-01-01
dc.identifierhttps://doi.org/10.1159/000213569
dc.identifier.citationGerontology. Basel: Karger, v. 40, n. 1, p. 13-17, 1994.
dc.identifier.issn0304-324X
dc.identifier.urihttp://repositorio.unifesp.br/11600/43728-
dc.description.abstractThe Ag-stained nucleolus organizer regions and the satellite association (SA) were studied in peripheral lymphocyte cultures derived from 10 patients with Alzheimer's disease (AD), 10 elderly controls and 10 young controls. Our results showed a significant lower frequency of Ag staining and SA in relation to the chromosome pair 21 in the AD patient group when compared with the elderly and young control groups. These results point to a reduction in the activity of ribosomal genes in the AD patient group.en
dc.format.extent13-17
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofGerontology
dc.rightsAcesso restrito
dc.subjectALZHEIMERS DISEASEen
dc.subjectCHROMOSOME 21en
dc.subjectNUCLEOLUS ORGANIZER REGIONSen
dc.subjectRIBOSOMAL GENESen
dc.subjectSATELLITE ASSOCIATIONen
dc.titleINVESTIGATION OF THE NUCLEOLAR ORGANIZER REGIONS IN ALZHEIMERS-DISEASEen
dc.typeArtigo
dc.rights.licensehttp://www.karger.com/Services/RightsPermissions
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationESCOLA PAULISTA MED,SETOR GERIATR & GERONTOL,SAO PAULO,BRAZIL
dc.description.affiliationUnifespESCOLA PAULISTA MED,SETOR GERIATR & GERONTOL,SAO PAULO,BRAZIL
dc.identifier.doi10.1159/000213569
dc.description.sourceWeb of Science
dc.identifier.wosWOS:A1994NG32200003
Appears in Collections:Artigo

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.