Please use this identifier to cite or link to this item:
|Title:||INVESTIGATION OF THE NUCLEOLAR ORGANIZER REGIONS IN ALZHEIMERS-DISEASE|
|Authors:||Payão, Spencer Luiz Marques [UNIFESP]|
Kormann-Bortolotto, Maria Helena [UNIFESP]
Toniolo Neto, João [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
NUCLEOLUS ORGANIZER REGIONS
|Citation:||Gerontology. Basel: Karger, v. 40, n. 1, p. 13-17, 1994.|
|Abstract:||The Ag-stained nucleolus organizer regions and the satellite association (SA) were studied in peripheral lymphocyte cultures derived from 10 patients with Alzheimer's disease (AD), 10 elderly controls and 10 young controls. Our results showed a significant lower frequency of Ag staining and SA in relation to the chromosome pair 21 in the AD patient group when compared with the elderly and young control groups. These results point to a reduction in the activity of ribosomal genes in the AD patient group.|
|Appears in Collections:||Artigo|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.