Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/43252
Title: Sudden unexpected death in an adolescent with epilepsy: All roads lead to the heart?
Authors: Pinto, Kylvia G. F. D.
Scorza, Fulvio Alexandre [UNIFESP]
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Martins, Luciana D.
Machado, Helio R.
Sakamoto, Américo Ceiki [UNIFESP]
Terra, Vera C.
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Keywords: sudden death
epilepsy
EEG
heart
Issue Date: 1-Mar-2011
Publisher: Via Medica
Citation: Cardiology Journal. Gdansk: Via Medica, v. 18, n. 2, p. 194-196, 2011.
Abstract: The incidence of sudden unexpected death in epilepsy (SUDEP) has been estimated from 0.5-1.4/1,000 person-years in people with treated epilepsy, and 9/1,000 person-years in candidates for epilepsy surgery. Potential risk factors for SUDEP include: age, early onset of epilepsy, duration of epilepsy, uncontrolled seizures, seizure type and winter temperatures. The arrythmogenic side-effect of antiepileptic drugs and seizures may increase the risk of SUDEP. In this report, we describe a patient with prolonged post-ictal tachycardia in EEG video recordings with a typical case of SUDEP: a 16-year-old boy with medically intractable complex partial seizures. Magnetic resonance imaging revealed left mesial temporal sclerosis. During non-invasive video-EEG monitoring, the patient presented a post-ictal heart rate increased for five hours. Two months after video-EEG, he died from SUDEP during a tonic-clonic secondary generalized seizure. The possibility of cardiac involvement in the pathogenesis of SUDEP has been suggested by many studies. Evaluation of this patient with EEG-video monitoring, including measurement of heart rate, contributed to an identification of ictal tachycardia that may have played a role in the SUDEP. Premature mortality seems to be increased in patients with epilepsy, and cardiac abnormalities may be a possible cause of SUDEP. (Cardiol J 2011; 18, 2: 194-196)
URI: http://repositorio.unifesp.br/11600/43252
ISSN: 1897-5593
Other Identifiers: https://journals.viamedica.pl/cardiology_journal/article/view/21274/16878
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