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|Title:||Sudden unexpected death in an adolescent with epilepsy: All roads lead to the heart?|
|Authors:||Pinto, Kylvia G. F. D.|
Scorza, Fulvio Alexandre [UNIFESP]
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Martins, Luciana D.
Machado, Helio R.
Sakamoto, Américo Ceiki [UNIFESP]
Terra, Vera C.
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
|Citation:||Cardiology Journal. Gdansk: Via Medica, v. 18, n. 2, p. 194-196, 2011.|
|Abstract:||The incidence of sudden unexpected death in epilepsy (SUDEP) has been estimated from 0.5-1.4/1,000 person-years in people with treated epilepsy, and 9/1,000 person-years in candidates for epilepsy surgery. Potential risk factors for SUDEP include: age, early onset of epilepsy, duration of epilepsy, uncontrolled seizures, seizure type and winter temperatures. The arrythmogenic side-effect of antiepileptic drugs and seizures may increase the risk of SUDEP. In this report, we describe a patient with prolonged post-ictal tachycardia in EEG video recordings with a typical case of SUDEP: a 16-year-old boy with medically intractable complex partial seizures. Magnetic resonance imaging revealed left mesial temporal sclerosis. During non-invasive video-EEG monitoring, the patient presented a post-ictal heart rate increased for five hours. Two months after video-EEG, he died from SUDEP during a tonic-clonic secondary generalized seizure. The possibility of cardiac involvement in the pathogenesis of SUDEP has been suggested by many studies. Evaluation of this patient with EEG-video monitoring, including measurement of heart rate, contributed to an identification of ictal tachycardia that may have played a role in the SUDEP. Premature mortality seems to be increased in patients with epilepsy, and cardiac abnormalities may be a possible cause of SUDEP. (Cardiol J 2011; 18, 2: 194-196)|
|Appears in Collections:||Artigo|
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