Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/42883
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dc.contributor.authorMedeiros, Eduardo Alexandrino Servolo [UNIFESP]
dc.date.accessioned2018-06-15T14:04:34Z-
dc.date.available2018-06-15T14:04:34Z-
dc.date.issued2008-10-01
dc.identifier.citationBrazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, p. 29-38, 2008.
dc.identifier.issn1413-8670
dc.identifier.urihttp://repositorio.unifesp.br/11600/42883-
dc.description.abstractHospital-acquired pneumonia (HAP) is a common and severe complication of critically ill patients. It has been associated with increased length of stay in the hospital and intensive care unit, as well as to high mortality rates. The potentially causative HAP pathogens can be suspected based on the assessment of a variety of risk factors, including the severity of the pneumonia itself, the presence of risk factors for specific organisms, length of hospital stay and prior antimicrobial use. The selection of empirical antimicrobial treatment of HAP has been challenged by the emergence and spread of multidrug-resistant organisms. Initial antimicrobial therapy should be guided against the most frequent HAP etiologic agents taking into the consideration the local frequency and susceptibility patterns exhibited by the most prevalent pathogens. Early and appropriate broad-spectrum antibiotic therapy should be prescribed with adequate doses to optimize antimicrobial efficacy. De-escalation of the antimicrobial regimen should be made as soon as the culture and susceptibility results become available. Efforts should also be made in limiting the time of antibiotic therapy.en
dc.format.extent29-38
dc.language.isoeng
dc.publisherContexto
dc.relation.ispartofBrazilian Journal Of Infectious Diseases
dc.rightsAcesso restrito
dc.subjectHospital-acquired pneumoniaen
dc.subjectventilator associated pneumoniaen
dc.subjectantimicrobial resistanceen
dc.subjectantimicrobial therapyen
dc.titleHospital-Acquired Pneumonia: Etiology and Antimicrobial Therapyen
dc.typeArtigo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv Fed Sao Paulo, Sch Med, UNIFESP EPM, Dept Med, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Sch Med, UNIFESP EPM, Hosp Epidemiol,Hosp Sao Paulo, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sch Med, UNIFESP EPM, Dept Med, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Sch Med, UNIFESP EPM, Hosp Epidemiol,Hosp Sao Paulo, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000266634000005
Appears in Collections:Artigo

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