Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/42597
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dc.contributor.authorQueiroz, Ana Beatriz Piazza [UNIFESP]
dc.contributor.authorFocchi, Gustavo Rubino de Azevedo [UNIFESP]
dc.contributor.authorDobo, Cristine [UNIFESP]
dc.contributor.authorGomes, Thiago Simao [UNIFESP]
dc.contributor.authorRibeiro, Daniel Araki [UNIFESP]
dc.contributor.authorOshima, Celina Tizuko Fujiyama [UNIFESP]
dc.date.accessioned2018-06-15T13:50:15Z-
dc.date.available2018-06-15T13:50:15Z-
dc.date.issued2010-07-01
dc.identifierhttp://ar.iiarjournals.org/content/30/7/2799.long
dc.identifier.citationAnticancer Research. Athens: Int Inst Anticancer Research, v. 30, n. 7, p. 2799-2803, 2010.
dc.identifier.issn0250-7005
dc.identifier.urihttp://repositorio.unifesp.br/11600/42597-
dc.description.abstractAim: To characterize the immunohistochemical expression of p27, p21(WAF/CiP1) and p16(INK4a) in normal oral epithelium, oral squamous pcipilloma and oral squamous cell carcinoma. Materials and Methods: hnmunohistochemical staining for p27, p21(WAF/Cip1) and p16(INK4a) was evaluated in 32 samples of normal oral squamous epithelium, 30 samples of oral squamous papilloma, and 34 samples of oral squamous cell carcinoma. Results: Statistically significant differences (p<0.05) were found in p27 expression when comparing ordinary mucosa and oral squamous papilloma with the oral squamous cell carcinoma samples. Regarding p21(WAF/Cip1) expression, no statistically significant differences (p>0.05) were noticed. In the same way, no significant statistically differences (p>0.05) were observed for p16(INK4a) among groups. Conclusion: Taken together, these findings indicate that p27 is closely involved in malignant transformation of oral mucosa cells, and may be a reliable biomarker for this purpose.en
dc.format.extent2799-2803
dc.language.isoeng
dc.publisherInt Inst Anticancer Research
dc.relation.ispartofAnticancer Research
dc.rightsAcesso aberto
dc.titleExpression of p27, p21(WAF/Cip1) and pl6(INK4a) in Normal Oral Epithelium, Oral Squamous Papilloma, and Oral Squamous Cell Carcinomaen
dc.typeArtigo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv Fed Sao Paulo, Dept Biociencias, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Patol, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Biociencias, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Patol, BR-11060001 Santos, SP, Brazil
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000280796400044
Appears in Collections:Artigo
Artigo

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