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dc.contributor.authorBaiocchi, Otavio Carvalho Guimarães [UNIFESP]
dc.contributor.authorColleoni, Gisele Wally Braga [UNIFESP]
dc.contributor.authorNavajas, Eduardo Vitor [UNIFESP]
dc.contributor.authorDuarte, Luiz Cláudio de Carvalho [UNIFESP]
dc.contributor.authorAlves, Antonio Correa [UNIFESP]
dc.contributor.authorAndrade, Ana Lúcia Sampaio Sgambatti de
dc.contributor.authorKerbauy, José [UNIFESP]
dc.contributor.authorOliveira, José Salvador Rodrigues de [UNIFESP]
dc.identifier.citationActa Oncologica. Oslo: Taylor & Francis As, v. 41, n. 2, p. 192-196, 2002.
dc.description.abstractTwenty cases of systemic non-Hodgkin's lymphoma (NHL) in HIV-infected patients were reviewed over a 10-year-period, divided into Group A, including 13 NHL cases treated before the highly active antiretroviral therapy (HAART) era, and Group B, including 7 patients who received HAART. A Kaplan-Meier survival curve was performed and log-rank was applied to assess statistical differences between the groups. In group A, the median CD4 count was 36 cells/mm(3). No complete remission was found. In group B, the median CD4 count was 137 cells/mm(3). Four patients (57.0%) are still alive and in complete remission. Group A had a median survival of 5 months and group B 31 months (p = 0.0032). Our results are in agreement with recent reports in that a higher CD4 count and better immune status achieved with HAART is predictive of a better outcome. We found that HAART in combination with chemotherapy improves overall survival of NHL patients without increasing adverse effects.en
dc.publisherTaylor & Francis As
dc.relation.ispartofActa Oncologica
dc.rightsAcesso aberto
dc.titleImpact of highly active antiretroviral therapy in the treatment of HIV-infected patients with systemic non-Hodgkin's lymphomaen
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.description.affiliationUniv Fed Sao Paulo, Hematol & Transfus Serv, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Pathol, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Goias, Dept Epidemiol, Goiania, Go, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Hematol & Transfus Serv, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Pathol, Sao Paulo, Brazil
dc.description.sourceWeb of Science
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