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Title: Analysis of the clonal diversity of Staphylococcus aureus methicillin-resistant strains isolated at João Pessoa, state of Paraíba, Brazil
Authors: Santos Filho, Lauro
Sader, Helio Silva [UNIFESP]
Bortolotto, Vania I [UNIFESP]
Gontijo Filho, Paulo P
Pignatari, Antonio Carlos Campos [UNIFESP]
UFPb Departamento de Ciências Farmacêuticas
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do Rio de Janeiro, nstituto de Microbiologia
Keywords: Staphylococcus aureus
molecular epidemiology
antimicrobial resistance
Issue Date: 1-Feb-1996
Publisher: Instituto Oswaldo Cruz, Ministério da Saúde
Citation: Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 91, n. 1, p. 101-105, 1996.
Abstract: To investigate the clonal diversity of Staphylococcus aureus strains isolated at João Pessoa, State of Paraíba, Brazil, digested genomic DNA were studied by pulsed-field gel electrophoresis (PFGE) in nine methicillin-resistant strains (MRSA) and three methicillin-sensitive strains (MSSA), selected among 67 isolates based on their antimicrobial susceptibility and epidemiology. The isolates were obtained between April and November 1992 from the Hospital of the Federal University of Paraíba, located in João Pessoa. Two MRSA isolates from the Oswaldo Cruz Hospital, São Paulo, Brazil, including an epidemic strain previously detected from different hospitals at the country were used as control. Five different patterns, were demonstrated by MRSA isolated in João Pessoa and these patterns were described in several epidemiologically unrelated hospitals in São Paulo. Our results suggest the interstate dissemination of a MRSA clone in João Pessoa which is similar to that described in other cities of Brazil.
ISSN: 0074-0276
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Appears in Collections:Artigo

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