Please use this identifier to cite or link to this item:
|Title:||First Proposed Panels on Acute Leukemia for Four-Color Immunophenotyping by Flow Cytometry from the Brazilian Group of Flow Cytometry-GBCFLUX|
|Authors:||Ikoma, Maura R. V.|
Sandes, Alex F. [UNIFESP]
Thiago, Leandro S.
Cavalcanti Junior, Geraldo B.
Lorand-Metze, Irene G. H.
Costa, Elaine S.
Santos-Silva, Maria C.
Bacal, Nydia S.
Yamamoto, Mihoko [UNIFESP]
Souto, Elizabeth X.
Hosp Amaral Carvalho
Universidade Federal de São Paulo (UNIFESP)
Brazilian Natl Canc Inst INCa
Univ Fed Rio Grande do Norte
Universidade Estadual de Campinas (UNICAMP)
Universidade Federal do Rio de Janeiro (UFRJ)
Lab Diagnost Amer
Universidade Federal de Santa Catarina (UFSC)
Hosp Israelita Albert Einstein
acute leukemia panel
acute lymphoblastic leukemia
acute myeloblastic leukemia
|Citation:||Cytometry Part B-clinical Cytometry. Hoboken: Wiley-Blackwell, v. 88, n. 3, p. 194-203, 2015.|
|Abstract:||Multiparameter flow cytometry is a highly sensitive, fast, and specific diagnostic technology with a wide range of applicability in hematology. Although well-established eight-color immunophenotyping panels are already available, most Brazilian clinical laboratories are equipped with four-color flow cytometer facilities. Based on this fact, the Brazilian Group of Flow Cytometry (Grupo Brasileiro de Citometria de Fluxo, GBCFLUX) for standardization of clinical flow cytometry has proposed an antibody panel designed to allow precise diagnosis and characterization of acute leukemia (AL) within resource-restricted areas. Morphological analysis of bone marrow smears, together with the screening panel, is mandatory for the primary identification of AL. the disease-oriented panels proposed here are divided into three levels of recommendations (mandatory, recommendable, and optional) in order to provide an accurate final diagnosis, as well as allow some degree of flexibility based on available local resources and patient-specific needs. the proposed panels will be subsequently validated in an interlaboratory study to evaluate its effectiveness on the diagnosis and classification of AL. (Assoc editor comm. 2). (c) 2015 International Clinical Cytometry Society|
|Appears in Collections:||Em verificação - Geral|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.