Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/38924
Title: Peripheral nerve regeneration with conduits: use of vein tubes
Authors: Sabongi, Rodrigo Guerra [UNIFESP]
Fernandes, Marcela [UNIFESP]
Santos, João Baptista Gomes dos [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Keywords: peripheral nerve injury
nerve graft
nerve conduit
Wallerian degeneration
neurotrophic factors
veins
autografts
nerve regeneration
Issue Date: 1-Apr-2015
Publisher: Shenyang Editorial Dept Neural Regeneration Res
Citation: Neural Regeneration Research. Shenyang: Shenyang Editorial Dept Neural Regeneration Res, v. 10, n. 4, p. 529-533, 2015.
Abstract: Treatment of peripheral nerve injuries remains a challenge to modern medicine due to the complexity of the neurobiological nerve regenerating process. There is a greater challenge when the transected nerve ends are not amenable to primary end-to-end tensionless neurorraphy. When facing a segmental nerve defect, great effort has been made. to develop an alternative to the autologous nerve graft in order to circumvent morbidity at donor site, such as neuroma formation, scarring and permanent loss of function. Tubolization techniques have been developed to bridge nerve gaps and have been extensively studied in numerous:experimental and clinical trials. the use of a conduit intends to act as a vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration. Among several conduits, vein tubes were validated for clinical application with improving outcomes over the Years. This article aims to address the investigation and treatment of segmental nerve injury and draw the current panorama on the use of vein tubes as an autogenous nerve conduit.
URI: http://repositorio.unifesp.br/handle/11600/38924
ISSN: 1673-5374
Other Identifiers: http://dx.doi.org/10.4103/1673-5374.155428
Appears in Collections:Em verificação - Geral

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