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Title: Influence of Microelement Concentration on the Intensity of Alcohol Withdrawal Syndrome
Authors: Prior, Pedro Luis [UNIFESP]
Vaz, Marta Jezierski
Ramos, Anna Carolina [UNIFESP]
Fernandes Galduroz, Jose Carlos [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Ctr Referencia Tratamento Alcool Tabaco & Outras
Issue Date: 1-Mar-2015
Publisher: Oxford Univ Press
Citation: Alcohol and Alcoholism. Oxford: Oxford Univ Press, v. 50, n. 2, p. 152-156, 2015.
Abstract: Aims: To establish a nutritional and constitutional profile concerning the micronutrient plasma concentration of patients who suffer from AWS. Method: Observational case control study to determine whether patients who exhibited symptoms of AWS (N = 60) had micronutrient plasmatic concentration deficiencies when compared with healthy controls (N = 34). Results: There were statistically significant differences between the concentrations of nutrients that are correlated with glutamate hyperactivity (zinc, magnesium and folate/vitamin B12/homocysteine). Conclusion: Evidence from literature and our experiment suggests that brain activity, especially the glutamatergic system, might be directly involved in micronutrient concentrations. Therefore, their supplementation to the AWS patient might improve symptom evolution.
ISSN: 0735-0414
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Appears in Collections:Artigo

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