Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/38835
Title: Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children
Authors: Alvarenga, Pedro G.
Cesar, Raony C.
Leckman, James F.
Moriyama, Tais S.
Torres, Albina R.
Bloch, Michael H.
Coughlin, Catherine G.
Hoexter, Marcelo Q.
Manfro, Gisele G.
Polanczyk, Guilherme V.
Miguel, Euripedes C.
Rosario, Maria C. do [UNIFESP]
Universidade de São Paulo (USP)
CNPq
Yale Univ
Univ Fed Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
Keywords: Epidemiology
Family history
Obsessive-compulsive disorder
School children
Issue Date: 1-Mar-2015
Publisher: Elsevier B.V.
Citation: Journal of Psychiatric Research. Oxford: Pergamon-Elsevier B.V., v. 62, p. 108-114, 2015.
Abstract: Background: Obsessive-compulsive disorder can be expressed as four potentially overlapping obsessive-compulsive symptom (OCS) dimensions (OCSD) (symmetry/ordering, contamination/cleaning, aggressive/sexual/religious and collecting/hoarding). in clinical samples, some dimensions are more familial and associated with increased psychiatric comorbidity and malfunctioning. However, data concerning OCS and OCSD are scarce in non-clinical samples, particularly among children. the present study aims to estimate: (1) the prevalence and sex/age distribution of OCS/OCSD in a community-based sample of schoolchildren; (2) the association between OCS and additional clinical factors; and (3) the degree of familial aggregation of OCS/OCSD.Methods: OCS and OCSD were evaluated in 9937 Brazilian school-children (6-12 years-old) and their biological relatives using the Family History Screen. Data analyses included gradient estimated equations and post-hoc tests.Results: We included data on 9937 index-children, 3305 siblings (13-18 years-old), and 16,218 parents. Biological mothers were the informants in 87.6% of the interviews. OCS were present in 14.7% of the index-children; 15.6% of their siblings; 34.6% of their mothers and 12.1% of their fathers. the prevalence of OCS and each of the OCSD gradually increased from ages 6 to 12 years. Overall, OCS in children were associated with the presence of other psychiatric symptoms, as well as behavioral/school impairment. OCS and each of the four OCSD aggregated significantly within families.Conclusions: OCS are prevalent and associated with psychiatric symptoms and clinical impairment among school-aged children. OCSD aggregate within families in a dimension-specific fashion. These findings suggest a natural continuum between OCS and OCD with regard to their dimensional character. (C) 2015 Elsevier B.V. All rights reserved.
URI: http://repositorio.unifesp.br/handle/11600/38835
ISSN: 0022-3956
Other Identifiers: http://dx.doi.org/10.1016/j.jpsychires.2015.01.018
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