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Title: High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results
Authors: Salum, Giovanni Abrahão
Gadelha, Ary [UNIFESP]
Pan, Pedro Mario [UNIFESP]
Moriyama, Tais Silveira [UNIFESP]
Graeff-Martins, Ana Soledade
Tamanaha, Ana Carina [UNIFESP]
Alvarenga, Pedro
Krieger, Fernanda Valle
Fleitlich-Bilyk, Bacy
Jackowski, Andrea Parolin [UNIFESP]
Sato, Joao Ricardo
Brietzke, Elisa [UNIFESP]
Polanczyk, Guilherme Vanoni
Brentani, Helena
Mari, Jair de Jesus [UNIFESP]
Rosario-Campos, Maria Conceicao do [UNIFESP]
Manfro, Gisele Gus
Bressan, Rodrigo Affonseca [UNIFESP]
Mercadante, Marcos Tomanik [UNIFESP]
Miguel, Euripedes Constantino
Rohde, Luis Augusto
Natl Inst Dev Psychiat Children & Adolescents INC
Univ Fed Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Universidade Federal do ABC (UFABC)
Keywords: longitudinal
Issue Date: 1-Mar-2015
Publisher: Wiley-Blackwell
Citation: International Journal of Methods in Psychiatric Research. Hoboken: Wiley-Blackwell, v. 24, n. 1, p. 58-73, 2015.
Abstract: The objective of this study is to present the rationale, methods, design and preliminary results from the High Risk Cohort Study for the Development of Childhood Psychiatric Disorders. We describe the sample selection and the components of each phases of the study, its instruments, tasks and procedures. Preliminary results are limited to the baseline phase and encompass: (i) the efficacy of the oversampling procedure used to increase the frequency of both child and family psychopathology; (ii) interrater reliability and (iii) the role of differential participation rate. A total of 9937 children from 57 schools participated in the screening procedures. From those 2512 (random =958; high risk =1554) were further evaluated with diagnostic instruments. the prevalence of any child mental disorder in the random strata and high-risk strata was 19.9% and 29.7%. the oversampling procedure was successful in selecting a sample with higher family rates of any mental disorders according to diagnostic instruments. Interrater reliability (kappa) for the main diagnostic instrument range from 0.72 (hyperkinetic disorders) to 0.84 (emotional disorders). the screening instrument was successful in selecting a sub-sample with high risk for developing mental disorders. This study may help advance the field of child psychiatry and ultimately provide useful clinical information. Copyright (c) 2014 John Wiley & Sons, Ltd.
ISSN: 1049-8931
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