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|Title:||Spectral-Domain Optical Coherence Tomography Measurements of Choroidal Thickness and Outer Retinal Disruption in Macular Telangiectasia Type 2|
|Authors:||Nunes, Renata Portella [UNIFESP]|
Amorim Garcia Filho, Carlos Alexandre de [UNIFESP]
Thorell, Mariana R.
Abbey, Ashkan M.
Kuriyan, Ajay E.
Modi, Yasha S.
Rosenfeld, Philip J.
Universidade Federal de São Paulo (UNIFESP)
William Beaumont Hosp
Midwest Eye Inst
|Citation:||Ophthalmic Surgery Lasers & Imaging Retina. Thorofare: Slack Inc, v. 46, n. 2, p. 162-170, 2015.|
|Abstract:||BACKGROUND and OBJECTIVE: To evaluate subfoveal choroidal thickness (CT) and the extent of outer retinal disruption in patients with macular telangiectasia type 2 (MacTel2) compared with healthy eyes.PATIENTS and METHODS: in this prospective, observational, cohort study, 62 patients (62 eyes) with MacTel2 and 130 healthy controls (130 eyes) underwent a complete ophthalmological examination, spectraldomain optical coherence tomography (SD-OCT) imaging, and axial length measurements. Patients in the study group also underwent color fundus photography, fundus autofluorescence, and fluorescein angiography. En face SD-OCT imaging was used to assess abnormalities involving the photoreceptor inner segment/outer segment/ellipsoid zone (IS/OS/EZ).RESULTS: After adjusting for age and axial length, the authors found that eyes with MacTel2 had a mean CT measurement that was greater than control eyes (P = .007). There was a negative correlation between the visual acuity and the area of IS/OS/EZ damage (P = .009), but no statistically significant correlation was seen between CT and the area of IS/OS/EZ damage.CONCLUSION: Eyes with MacTel2 were found to have thicker CT measurements than control eyes. While the extent of IS/OS/EZ disruption correlated with the loss of visual acuity, this damage did not correlate with CT measurements.|
|Appears in Collections:||Em verificação - Geral|
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