Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/38565
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dc.contributor.authorYadav, Mayank
dc.contributor.authorGenereux, Philippe
dc.contributor.authorPalmerini, Tullio
dc.contributor.authorCaixeta, Adriano [UNIFESP]
dc.contributor.authorMadhavan, Mahesh V.
dc.contributor.authorXu, Ke
dc.contributor.authorBrener, Sorin J.
dc.contributor.authorMehran, Roxana
dc.contributor.authorStone, Gregg W.
dc.date.accessioned2016-01-24T14:38:19Z-
dc.date.available2016-01-24T14:38:19Z-
dc.date.issued2015-01-01
dc.identifierhttp://dx.doi.org/10.1002/ccd.25396
dc.identifier.citationCatheterization and Cardiovascular Interventions. Hoboken: Wiley-Blackwell, v. 85, n. 1, p. 1-10, 2015.
dc.identifier.issn1522-1946
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/38565-
dc.description.abstractObjectiveWe sought to investigate the relationship between the SYNTAX score (SS) and stent thrombosis (ST) in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) undergoing percutaneous coronary intervention (PCI).BackgroundThe relationship between the SS and ST is undetermined.MethodsWe stratified 2,627 patients undergoing PCI in the ACUITY trial by SS tertile according to the current population (true tertiles, SS <7, SS = 7-12, and SS >12) and by the SYNTAX trial (original SYNTAX tertiles, SS <23, SS = 23-32, and SS >32). Thirty-day and 1-year rates of definite/probable ST were determined for each tertile.ResultsA total 30 (1.1%) and 41 (1.6%) definite/probable ST events occurred by 30 days and 1 year, respectively. When stratified by true tertiles, 30-day and 1-year rates of definite/probable ST were significantly greater in the highest tertile (SS >12; 2.0% and 2.8%) compared with the intermediate (SS = 7-12; 0.7% and 1.1%) and lowest tertiles (SS <7; 0.6% and 0.7%), P = 0.007 and P = 0.0009, respectively. When stratified by original SYNTAX tertiles, 30-day and 1-year rates of definite/probable ST were significantly greater in the highest (SS >32; 6.3% and 8.8%) and intermediate tertiles (SS = 23-32; 2.8% and 3.7%) compared with the lowest tertile (SS < 22; 0.8% and 1.2%), P <0.0001 for both. By multivariable analysis, the SS was an independent predictor for both 30-day and 1-year definite/probable ST.ConclusionsIn patients with NSTE-ACS undergoing PCI, the extent and severity of CAD, as assessed by the SS before revascularization, was strongly associated with the occurrence of ST both at 30 days and 1 year. (c) 2014 Wiley Periodicals, Inc.en
dc.description.sponsorshipAbbott Vascular
dc.description.sponsorshipDoris Duke Charitable Foundation to Columbia University
dc.format.extent1-10
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofCatheterization and Cardiovascular Interventions
dc.rightsAcesso aberto
dc.subjectSYNTAX scoreen
dc.subjectstent thrombosisen
dc.subjectACSen
dc.subjectNSTE-ACSen
dc.subjectNSTEMIen
dc.titleSYNTAX Score and the Risk of Stent Thrombosis After Percutaneous Coronary Intervention in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes: An ACUITY Trial Substudyen
dc.typeArtigo
dc.rights.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institutionCardiovasc Res Fdn
dc.contributor.institutionColumbia Univ
dc.contributor.institutionUniv Montreal
dc.contributor.institutionUniv Bologna
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionNew York Methodist Hosp
dc.contributor.institutionMt Sinai Med Ctr
dc.description.affiliationCardiovasc Res Fdn, New York, NY USA
dc.description.affiliationColumbia Univ, Med Ctr, New York Presbyterian Hosp, New York, NY 10022 USA
dc.description.affiliationUniv Montreal, Hop Sacre Coeur Montreal, Montreal, PQ, Canada
dc.description.affiliationUniv Bologna, Ist Cardiol, I-40126 Bologna, Italy
dc.description.affiliationUniversidade Federal de São Paulo, Hosp Israelita Albert Einstein, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, São Paulo, Brazil
dc.description.affiliationNew York Methodist Hosp, New York, NY USA
dc.description.affiliationMt Sinai Med Ctr, New York, NY 10029 USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Hosp Israelita Albert Einstein, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, São Paulo, Brazil
dc.identifier.doi10.1002/ccd.25396
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000346479900007
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