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Title: Assessment of fatigue in a large series of 1492 Brazilian patients with Spondyloarthritis
Authors: Bianchi, Washington A.
Elias, Fernanda R.
Carneiro, Sueli
Bortoluzzo, Adriana B.
Goncalves, Celio R.
Braga da Silva, Jose Antonio
Ximenes, Antonio Carlos
Bertolo, Manoel B.
Ribeiro, Sandra L. E.
Keiserman, Mauro
Skare, Thelma L.
Menin, Rita
Azevedo, Valderilio F.
Vieira, Walber P.
Albuquerque, Elisa N.
Bonfiglioli, Rubens
Campanholo, Cristiano
Carvalho, Hellen M. S.
Costa, Izaias P.
Duarte, Angela P.
Kohem, Charles L.
Leite, Nocy H.
Lima, Sonia A. L.
Meirelles, Eduardo S.
Pereira, Ivanio A.
Pinheiro, Marcelo M. [UNIFESP]
Polito, Elizandra
Resende, Gustavo G.
Rocha, Francisco Airton C.
Santiago, Mittermayer B.
Sauma, Maria de Fatima L. C.
Valim, Valeria
Sampaio-Barros, Percival D.
Santa Casa Rio de Janeiro
Universidade Federal do Rio de Janeiro (UFRJ)
Universidade do Estado do Rio de Janeiro (UERJ)
Insper Inst Educ & Res
Universidade de São Paulo (USP)
Universidade de Brasília (UnB)
Hosp Geral Goiania
Universidade Estadual de Campinas (UNICAMP)
Univ Fed Amazonas
Pontificia Univ Catolica Porto Alegre
Hosp Evangel Curitiba
Univ Fed Parana
Hosp Geral Fortaleza
Pontificia Univ Catolica Campinas
Santa Casa São Paulo
Hosp Base
Universidade Federal de Mato Grosso do Sul (UFMS)
Universidade Federal de Pernambuco (UFPE)
Univ Fed Rio Grande do Sul
Fac Med Souza Marques
Hosp Servidor Publ Estadual
Universidade Federal de Santa Catarina (UFSC)
Universidade Federal de São Paulo (UNIFESP)
Santa Casa Belo Horizonte
Universidade Federal de Minas Gerais (UFMG)
Escola Med & Saude Publ Salvador
Fed Univ Para
Univ Fed Espirito Santo
Keywords: Spondyloarthritis
Disease activity
Quality of life
Issue Date: 1-Nov-2014
Publisher: Springer
Citation: Modern Rheumatology. New York: Springer, v. 24, n. 6, p. 980-984, 2014.
Abstract: Background. the aim of the present study was to analyze the score of fatigue in a large cohort of Brazilian patients with SpA, comparing different disease patterns and its association with demographic and disease-specific variables.Methods. A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyloarthropathies Study Group (ESSG) criteria, attended at 29 reference centers. Clinical and demographic variables were recorded. Fatigue was evaluated using the first item of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) questionnaire.Results. the mean BASDAI fatigue score was 4.20 +/- 2.99. There was no significant difference in the fatigue score between the different SpA. Fatigue was higher in female patients (p < 0.001), with mixed (axial vertical bar peripheral) involvement (p < 0.001) and in those who did not practice exercises (p < 0.001). Higher scores of fatigue were significantly associated with inflammatory low back pain (p = 0.013), alternating buttock pain (p = 0.001), cervical pain (p = 0.001), and hip involvement (p = 0.005). Fatigue presented a moderate positive statistical correlation with Bath Ankylosing Spondylitis Functional Index (BASFI) (0.469; p < 0.001) and Ankylosing Spondylitis Quality of Life (0.462; p < 0.001).Conclusion. in this large series of Brazilian SpA patients, higher fatigue scores were associated with female gender, sedentary, worse functionality, and quality of life.
ISSN: 1439-7595
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