Please use this identifier to cite or link to this item:
Title: Assessment of five different guideline indication criteria for spirometry, including modified GOLD criteria, in order to detect COPD: data from 5,315 subjects in the PLATINO study
Authors: Luize, Ana P. [UNIFESP]
Menezes, Ana Maria B.
Perez-Padilla, Rogelio
Muino, Adriana
Victorina Lopez, Maria
Valdivia, Gonzalo
Lisboa, Carmem
Montes de Oca, Maria
Talamo, Carlos
Celli, Bartolome
Nascimento, Oliver Augusto [UNIFESP]
Gazzotti, Mariana Rodrigues [UNIFESP]
Jardim, José Roberto [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Univ Fed Pelotas
Inst Nacl Enfermedades Resp
Univ Republica
Pontificia Univ Catolica Chile
Cent Univ Venezuela
Harvard Univ
Issue Date: 30-Oct-2014
Publisher: Nature Publishing Group
Citation: Npj Primary Care Respiratory Medicine. New York: Nature Publishing Group, v. 24, 5 p., 2014.
Abstract: BACKGROUND: Spirometry is the gold standard for diagnosing chronic obstructive pulmonary disease (COPD). Although there are a number of different guideline criteria for deciding who should be selected for spirometric screening, to date it is not known which criteria are the best based on sensitivity and specificity.AIMS: Firstly, to evaluate the proportion of subjects in the PLATINO Study that would be recommended for spirometry testing according to Global initiative for Obstructive Lung Disease (GOLD)-modified, American College of Chest Physicians (ACCP), National Lung Health Education Program (NLHEP), GOLD and American Thoracic Society/European Respiratory Society (ATS/ERS) criteria. Secondly, we aimed to compare the sensitivity, specificity, and positive predictive and negative predictive values, of these five different criteria.METHODS: Data from the PLATINO study included information on respiratory symptoms, smoking and previous spirometry testing. the GOLD-modified spirometry indication criteria are based on three positive answers out of five questions: the presence of cough, phlegm in the morning, dyspnoea, age over 40 years and smoking status.RESULTS: Data from 5,315 subjects were reviewed. Fewer people had an indication for spirometry (41.3%) according to the GOLD-modified criteria, and more people had an indication for spirometry (80.4%) by the GOLD and ATS/ERS criteria. A low percentage had previously had spirometry performed: GOLD-modified (14.5%); ACCP (13.2%); NLHEP (12.6%); and GOLD and ATS/ERS (12.3%). the GOLD-modified criteria showed the least sensitivity (54.9) and the highest specificity (61.0) for detecting COPD, whereas GOLD and ATS/ERS criteria showed the highest sensitivity (87.9) and the least specificity (20.8).CONCLUSION: There is a considerable difference in the indication for spirometry according to the five different guideline criteria. the GOLD-modified criteria recruit less people with the greatest sum of sensitivity and specificity.
ISSN: 2055-1010
Other Identifiers:
Appears in Collections:Em verificação - Geral

Files in This Item:
File Description SizeFormat 
WOS000345390600001.pdf245.52 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.