Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/37420
Title: Predictive factors of overall quality of life in advanced cancer patients using EORTC QLQ-C30
Authors: Cramarossa, Gemma
Zeng, Liang
Zhang, Liying
Tseng, Ling-Ming
Hou, Ming-Feng
Fairchild, Alysa
Vassiliou, Vassilios
Jesus-Garcia, Reynaldo [UNIFESP]
El-Din, Mohamed A. Alm
Kumar, Aswin
Forges, Fabien
Chie, Wei-Chu
Sahgal, Arjun
Lam, Henry
Pulenzas, Natalie
Chow, Edward
Univ Toronto
Natl Yang Ming Univ
Kaohsiung Med Univ Hosp
Cross Canc Inst
Bank Cyprus
Universidade Federal de São Paulo (UNIFESP)
Tanta Univ Hosp
Reg Canc Ctr
St Etienne Univ Hosp
Natl Taiwan Univ
Keywords: advanced cancer
EORTC QLQ-C30
metastatic cancer
quality of life
symptom control
Issue Date: 1-Feb-2014
Publisher: Expert Reviews
Citation: Expert Review of Pharmacoeconomics & Outcomes Research. London: Expert Reviews, v. 14, n. 1, p. 139-146, 2014.
Abstract: Objective: To identify which domains/symptoms from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) were predictive of overall quality of life (QoL) in advanced cancer patients. Methods: Four hundred and forty seven patients with brain metastases or bone metastases from seven countries were enrolled with regression analysis to determine the predictive value of the QLQ-C30 functional/symptom scores for patient reported overall QoL (question 30), overall health (question 29) and the global health status domain (questions 29 and 30). Results: Worse role functioning, social functioning, fatigue and financial problems were the most significant predictive factors for worse QoL. in the bone metastases subgroup (n = 400), role functioning, fatigue and financial problems were the most significant predictors. in patients with brain metastases (n = 47), none of the EORTC domains significantly predicted worse QOL. Conclusion: Deterioration of certain QLQ-C30 functional/symptom scores significantly contributes to worse QoL, overall health and global health status.
URI: http://repositorio.unifesp.br/handle/11600/37420
ISSN: 1473-7167
Other Identifiers: http://dx.doi.org/10.1586/14737167.2014.864560
Appears in Collections:Em verificação - Geral

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