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Title: Analysis of Short-Term Change in Subfoveal Choroidal Thickness in Eyes With Age-Related Macular Degeneration Using Optical Coherence Tomography
Authors: Fein, Jordana G.
Branchini, Lauren A.
Manjunath, Varsha
Regatieri, Caio V. [UNIFESP]
Fujimoto, James G.
Duker, Jay S.
Tufts Med Ctr
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 1-Jan-2014
Publisher: Slack Inc
Citation: Ophthalmic Surgery Lasers & Imaging. Thorofare: Slack Inc, v. 45, n. 1, p. 32-37, 2014.
Abstract: BACKGROUND and OBJECTIVE: To measure the sub-foveal choroidal thickness in patients with age-related macular degeneration (AMD) over 6 months.PATIENTS and METHODS: A retrospective, observational study of patients with AMD followed up for 6 months at the New England Eye Center. Baseline and 6-month follow-up subfoveal choroidal thickness was measured using spectral-domain OCT and compared.RESULTS: for the entire cohort, there was statistically significant thinning of the subfoveal choroidal thickness at 6 months compared to baseline that was driven by the cohort of patients with neovascular AMD (181.2 +/- 75 mu m to 173.4 +/- 63 mu m; P=.049).CONCLUSION: There was a statistically significant decrease in subfoveal choroidal thickness observed in this cohort of patients with AMD over 6 months, but it was driven by the subgroup of patients with neovascular age-related macular degeneration.
ISSN: 1542-8877
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