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Title: Targeting the Inflammatory Pathway as a Therapeutic Tool for Major Depression
Authors: Noto, Cristiano [UNIFESP]
Rizzo, Lucas Bortolotto [UNIFESP]
Mansur, Rodrigo Barbachan [UNIFESP]
McIntyre, Roger S.
Maes, Michael
Brietzke, Elisa [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Univ Toronto
Deakin Univ
Chulalongkorn Univ
Keywords: Depression
Issue Date: 1-Jan-2014
Publisher: Karger
Citation: Neuroimmunomodulation. Basel: Karger, v. 21, n. 2-3, p. 131-139, 2014.
Abstract: In the last decades convergent findings from several lines of evidence has revealed a robust association between major depressive disorder (MDD) and inflammatory pathways. Despite this, the translation of these findings into new and better treatments for MDD has not occurred. the objective of this study is to comprehensively review what is already known with reasonable certainty on inflammatory pathways in MDD, to clarify some points that have been insufficiently studied and to discuss the implications of these findings for future studies targeting inflammatory pathways as a therapeutic tool for individuals with MDD. (C) 2014 S. Karger AG, Basel
ISSN: 1021-7401
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