Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/37134
Full metadata record
DC FieldValueLanguage
dc.contributor.authorWasinski, Frederick [UNIFESP]
dc.contributor.authorGregnani, Marcos F.
dc.contributor.authorOrnellas, Fabio H.
dc.contributor.authorBacurau, Aline V. N.
dc.contributor.authorCamara, Niels O. [UNIFESP]
dc.contributor.authorAraujo, Ronaldo C. [UNIFESP]
dc.contributor.authorBacurau, Reury F. P. [UNIFESP]
dc.date.accessioned2016-01-24T14:34:55Z
dc.date.available2016-01-24T14:34:55Z
dc.date.issued2014-01-01
dc.identifierhttp://dx.doi.org/10.1155/2014/326803
dc.identifier.citationMediators of Inflammation. New York: Hindawi Publishing Corporation, 10 p., 2014.
dc.identifier.issn0962-9351
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37134
dc.description.abstractGlucose and glutamine are important energetic and biosynthetic nutrients for T and B lymphocytes. These cells consume both nutrients at high rates in a function-dependentmanner. in other words, the pathways that control lymphocyte function and survival directly control the glucose and glutamine metabolic pathways. Therefore, lymphocytes in different functional states reprogram their glucose and glutamine metabolism to balance their requirement for ATP and macromolecule production. the tight association between metabolism and function in these cells was suggested to introduce the possibility of several pathologies resulting from the inability of lymphocytes to meet their nutrient demands under a given condition. in fact, disruptions in lymphocyte metabolism and function have been observed in different inflammatory, metabolic, and autoimmune pathologies. Regular physical exercise and physical activity offer protection against several chronic pathologies, and this benefit has been associated with the anti-inflammatory and immunomodulatory effects of exercise/physical activity. Chronic exercise induces changes in lymphocyte functionality and substrate metabolism. in the present review, we discuss whether the beneficial effects of exercise on lymphocyte function in health and disease are associated with modulation of the glucose and glutamine metabolic pathways.en
dc.format.extent10
dc.language.isoeng
dc.publisherHindawi Publishing Corporation
dc.relation.ispartofMediators of Inflammation
dc.rightsAcesso aberto
dc.titleLymphocyte Glucose and Glutamine Metabolism as Targets of the Anti-Inflammatory and Immunomodulatory Effects of Exerciseen
dc.typeResenha
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUniversidade Federal de São Paulo, Dept Biophys, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Med, Div Nephrol, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Arts Sci & Humanities, BR-03828000 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Phys Educ & Sport, Dept Biodynam Human Movement, BR-05508030 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Inst Biomed Sci, Lab Transplantat Immunobiol, Dept Immunol, BR-05508900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Biophys, BR-04023900 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Med, Div Nephrol, BR-04023900 São Paulo, Brazil
dc.identifier.fileWOS000337442400001.pdf
dc.identifier.doi10.1155/2014/326803
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000337442400001
Appears in Collections:Em verificação - Geral

Files in This Item:
File Description SizeFormat 
WOS000337442400001.pdf1.83 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.