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Title: Polymorphisms in schizophrenia candidate gene UFD1L may contribute to cognitive deficits
Authors: Ota, Vanessa K. [UNIFESP]
Berberian, Arthur A. [UNIFESP]
Gadelha, Ary [UNIFESP]
Santoro, Marcos L. [UNIFESP]
Ottoni, Gustavo L.
Matsuzaka, Camila T. [UNIFESP]
Mari, Jair J. [UNIFESP]
Melaragno, Maria I. [UNIFESP]
Lara, Diogo R.
Smith, Marilia A. C. [UNIFESP]
Belangero, Sintia I. [UNIFESP]
Bressan, Rodrigo A. [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Pontificia Univ Rio Grande Sul PUCRS
Keywords: Executive functions
Issue Date: 30-Aug-2013
Publisher: Elsevier B.V.
Citation: Psychiatry Research. Clare: Elsevier B.V., v. 209, n. 1, p. 110-113, 2013.
Abstract: We aimed to investigate UFD1L polymorphisms in schizophrenia and in relation to cognition. A total of 299 cases and 363 controls were genotyped, and 130 patients completed nine neuropsychological tests. We found that rs5992403 AA-genotype carriers showed lower scores on the set-shifting task. Therefore, UFD1L may participate in the core cognitive deficits observed in schizophrenia. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
ISSN: 0165-1781
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