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Title: Activation and involvement of the lateral-posterior nucleus of the thalamus after a single generalized tonic-clonic seizure
Authors: Sonoda, Eliza Yumi de Freitas [UNIFESP]
Cysneiros, Roberta Monterazzo
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Scorza, Fulvio Alexandre [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Univ Presbiteriana Mackenzie
Keywords: Neuronal activation
Cell excitability
Neuronal loss
Issue Date: 1-Jul-2013
Publisher: Elsevier B.V.
Citation: Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 28, n. 1, p. 104-107, 2013.
Abstract: The lateral-posterior thalamic nuclei (LP) have been shown to play an important role in controlling epileptic activity. in addition, thalamic atrophy and neuronal loss have been observed in epilepsy. the objective of this study was to investigate whether lateral-posterior neuronal activation may be observed shortly after a single generalized seizure in rats submitted to the pilocarpine model of epilepsy. the results showed an increased lateral-posterior activation as soon as the seizure occurred, suggesting that neuronal loss in the thalamus is not only the consequence of chronic epilepsy. (C) 2013 Elsevier Inc. All rights reserved.
ISSN: 1525-5050
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Appears in Collections:Artigo

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