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Title: Sudden unexpected death in epilepsy: From the lab to the clinic setting
Authors: Terra, Vera C.
Cysneiros, Roberta Monterazzo [UNIFESP]
Cavalheiro, Esper A. [UNIFESP]
Scorza, Fulvio A. [UNIFESP]
Universidade de São Paulo (USP)
Univ Presbiteriana Mackenzie
Universidade Federal de São Paulo (UNIFESP)
Keywords: Epilepsy
Sudden death
Risk factors
Issue Date: 1-Mar-2013
Publisher: Elsevier B.V.
Citation: Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 26, n. 3, p. 415-420, 2013.
Abstract: Sudden unexpected death in epilepsy (SUDEP) is defined as sudden, unexpected, witnessed or unwitnessed, non-traumatic, and non-drowning death in a patient with epilepsy. Sudden unexpected death in epilepsy is probably the most common cause of epilepsy-related deaths. Many predisposing and initiating factors may coexist and contribute to SUDEP, but the mechanisms are poorly understood. Cardiac and respiratory deregulation seems to have a major role in SUDEP. Here, we review several advances in understanding the mechanisms involved in SUDEP.This article is part of a Special Issue entitled the Future of Translational Epilepsy Research. (c) 2012 Elsevier Inc. All rights reserved.
ISSN: 1525-5050
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