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Title: Sleep deprivation alters phosphorylated CREB levels in the amygdala: Relationship with performance in a fear conditioning task
Authors: Pinho, Nadine [UNIFESP]
Moreira, Karin Monteiro [UNIFESP]
Hipólide, Débora Cristina [UNIFESP]
Sinigaglia-Coimbra, Rita [UNIFESP]
Ferreira, Tatiana Lima
Nobrega, Jose N.
Tufik, Sergio [UNIFESP]
Menezes Oliveira, Maria Gabriela [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do ABC (UFABC)
Ctr Addict & Mental Hlth
Keywords: Memory
Contextual fear conditioning
Issue Date: 1-Jan-2013
Publisher: Elsevier B.V.
Citation: Behavioural Brain Research. Amsterdam: Elsevier B.V., v. 236, p. 221-224, 2013.
Abstract: We investigated the relationship between deficits in fear memory induced by sleep deprivation and pCREB expression in the basal and central nuclei of the amygdala. Sleep deprivation reduced pCREB expression in the central nucleus compared to control or sleep recovered groups, and in the basal nucleus only compared to sleep recovered group. Moreover, 24 h of sleep recovery prior to training prevented changes in both pCREB expression and performance. (C) 2012 Elsevier B.V. All rights reserved.
ISSN: 0166-4328
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Appears in Collections:Em verificação - Geral

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