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Title: Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People
Authors: Alves, Eduardo da Silva [UNIFESP]
Souza, Helton de Sá [UNIFESP]
Rosa, João Paulo Pereira [UNIFESP]
Lira, Fabio Santos de [UNIFESP]
Pimentel, Gustavo Duarte
Santos, Ronaldo Vagner Thomatieli dos [UNIFESP]
Oyama, Lila Missae [UNIFESP]
Dâmaso, Ana Raimunda [UNIFESP]
Nascimento, Claudia Maria da Penha Oller do [UNIFESP]
Viana, Valter Antonio Rocha [UNIFESP]
Boscolo, Rita Aurélia [UNIFESP]
Grassmann, Viviane [UNIFESP]
Santana, Marcos Gonçalves de [UNIFESP]
Tufik, Sergio [UNIFESP]
Mello, Marco Tulio de [UNIFESP]
Ctr Estudo Psicobiol Exercicio
Universidade Federal de São Paulo (UNIFESP)
Univ Extremo Sul Catarinense
Universidade Estadual de Campinas (UNICAMP)
Universidade Federal de Goiás (UFG)
Keywords: Aerobic capacity
Moderate training
Issue Date: 1-Dec-2012
Publisher: Georg Thieme Verlag Kg
Citation: Hormone and Metabolic Research. Stuttgart: Georg Thieme Verlag Kg, v. 44, n. 13, p. 975-979, 2012.
Abstract: Aging and physical inactivity are 2 factors that favour the development of cardiovascular disease, metabolic syndrome, obesity, and diabetes. in contrast, adopting a habitual moderate exercise routine may be a nonpharmacological treatment alternative for neuroendocrine aging disorders. We aimed to assess the effects of moderate exercise training on the metabolic profiles of elderly people with sedentary lifestyles. Fourteen sedentary, healthy, elderly male volunteers participated in a moderate training regimen for 60 min/day, 3 days/week for 24 weeks at a work rate equivalent to their ventilatory aerobic threshold. the environment was maintained at a temperature of 23 +/- 2 degrees C, with a humidity of 60 +/- 5 %. Blood samples for analysis were collected at 3 intervals: at baseline (1 week before training began), and 3 and 6 months after training. the training promoted increased aerobic capacity (relative VO2, and time and velocity to VO(2)max; (p < 0.05)) and reduced serum alpha-MSH (p < 0.05) after 3 months of training when compared with the baseline data. in addition, serum thyroid hormone (T3 and T4) was reduced after 6 months of training compared with baseline levels. Our results demonstrate that a moderate exercise training protocol improves the metabolic profile of older people, and metabolic adaptation is dependent on time.
ISSN: 0018-5043
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