Please use this identifier to cite or link to this item: http://repositorio.unifesp.br/handle/11600/35154
Title: Leptin as a link between the immune system and kidney-related diseases: leading actor or just a coadjuvant?
Authors: Moraes-Vieira, P. M. M.
Bassi, E. J.
Araujo, R. C. [UNIFESP]
Camara, N. O. S.
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Keywords: Foxp3
kidney
leptin
nephrology
Issue Date: 1-Aug-2012
Publisher: Wiley-Blackwell
Citation: Obesity Reviews. Hoboken: Wiley-Blackwell, v. 13, n. 8, p. 733-743, 2012.
Abstract: Food intake and nutritional status modify the physiological responses of the immune system to illness and infection and regulate the development of chronic inflammatory processes, such as kidney disease. Adipose tissue secretes immune-related proteins called adipokines that have pleiotropic effects on both the immune and neuroendocrine systems, linking metabolism and immune physiology. Leptin, an adipose tissue-derived adipokine, displays a variety of immune and physiological functions, and participates in several immune responses. Here, we review the current literature on the role of leptin in kidney diseases, linking adipose tissue and the immune system with kidney-related disorders. the modulation of this adipose hormone may have a major impact on the treatment of several immune- and metabolic-related kidney diseases.
URI: http://repositorio.unifesp.br/handle/11600/35154
ISSN: 1467-7881
Other Identifiers: http://dx.doi.org/10.1111/j.1467-789X.2012.00997.x
Appears in Collections:Em verificação - Geral

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.