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dc.contributor.authorScattolin, M. A. A. [UNIFESP]
dc.contributor.authorLin, J. [UNIFESP]
dc.contributor.authorPeruchi, M. M.
dc.contributor.authorRocha, A. J.
dc.contributor.authorMasruha, M. R. [UNIFESP]
dc.contributor.authorVilanova, L. C. P. [UNIFESP]
dc.identifier.citationJournal of Neuroradiology. Moulineaux Cedex 9: Masson Editeur, v. 38, n. 5, p. 313-318, 2011.
dc.description.abstractNeurocutaneous melanosis is a rare, congenital, non-inherited syndrome characterized by numerous and/or large congenital nevi with intracranial leptomeningeal melanocytosis. This report describes two patients, presenting with a giant congenital nevus involving, a major portion of the posterior trunk with satellite congenital nevi scattered all over the body, who developed seizures at 4 and 6 months of age, respectively. Changes in follow-up magnetic resonance (MR) examinations over an 8-year period were seen in case 1, while parenchymal melanocytic accumulation was reported in the region of the amygdala in case 2. These cases emphasize that neurocutaneous melanosis should be suspected in patients with giant congenital nevus with or without neurological symptoms. Also, neuroaxial MR screening should be performed in all cases and, ideally, before myelination of the brain to provide the highest sensitivity for detecting melanin deposits in the leptomeninges. (C) 2011 Elsevier Masson SAS. All rights reserved.en
dc.publisherMasson Editeur
dc.relation.ispartofJournal of Neuroradiology
dc.rightsAcesso restrito
dc.subjectNeurocutaneous melanosisen
dc.subjectGiant melanocytic nevusen
dc.titleNeurocutaneous melanosis: Follow-up and literature reviewen
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionSanta Casa de Misericordia São Paulo
dc.description.affiliationUniversidade Federal de São Paulo, UNIFESP, Dept Neurol & Neurosurg, BR-04023900 São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Dept Radiol, São Paulo, Brazil
dc.description.affiliationSanta Casa de Misericordia São Paulo, Deparment Radiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, UNIFESP, Dept Neurol & Neurosurg, BR-04023900 São Paulo, Brazil
dc.description.sourceWeb of Science
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