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|Title:||Cellular death but not genetic damage in oral mucosa cells after exposure to digital lateral radiography|
|Authors:||Ribeiro, Daniel A. [UNIFESP]|
Sannomiya, Eduardo K.
Pozzi, Renan [UNIFESP]
Miranda, Sandra R. [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
São Paulo Methodist Univ
|Keywords:||Buccal mucosa cells|
Digital lateral radiograph
|Citation:||Clinical Oral Investigations. Heidelberg: Springer Heidelberg, v. 15, n. 3, p. 357-360, 2011.|
|Abstract:||The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from individuals following digital lateral radiography. A total of 30 healthy patients (15 men and 15 women) indicated to the orthodontic therapy were submitted to digital lateral X-ray. Exfoliated oral mucosa cells were collected immediately before the X-ray exposure and after 10 days. the results pointed out no significant statistically differences (p > 0.05) of micronucleated oral mucosa cells. On the other hand, X-ray was able to increase other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis, and karyolysis. in summary, these data indicate that exposure to digital lateral radiography may not be a factor that induced chromosomal damage, but it is able to promote cytotoxicity.|
|Appears in Collections:||Em verificação - Geral|
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