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Title: Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses
Authors: Moraes, Luis Otavio Carvalho de [UNIFESP]
Lodi, Fabio Redivo [UNIFESP]
Gomes, Thiago Simao [UNIFESP]
Marques, Sergio Ricardo [UNIFESP]
Oshima, Celina Tizuko Fujiyama [UNIFESP]
Lancellotti, Carmen Lucia Penteado
Rodriguez-Vazquez, Jose Francisco
Merida-Velasco, Jose Ramon
Alonso, Luis Garcia [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Santa Casa São Paulo
Univ Complutense Madrid
Keywords: articular disc
temporomandibular joint
human foetuses
Issue Date: 1-Jan-2011
Publisher: Pagepress Publ
Citation: European Journal of Histochemistry. Pavia: Pagepress Publ, v. 55, n. 3, p. 127-130, 2011.
Abstract: The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. the gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.
ISSN: 1121-760X
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