Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/32490
Title: EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria
Authors: Ozen, Seza
Pistorio, Angela
Iusan, Silvia M.
Bakkaloglu, Aysin
Herlin, Troels
Brik, Riva
Buoncompagni, Antonella
Lazar, Calin
Bilge, Ilmay
Uziel, Yosef
Rigante, Donato
Cantarini, Luca
Hilario, Maria Odete [UNIFESP]
Silva, Clovis A.
Alegria, Mauricio
Norambuena, Ximena
Belot, Alexandre
Berkun, Yackov
Estrella, Amparo Ibanez
Olivieri, Alma Nunzia
Alpigiani, Maria Giannina
Rumba, Ingrida
Sztajnbok, Flavio
Tambic-Bukovac, Lana
Breda, Luciana
Al-Mayouf, Sulaiman
Mihaylova, Dimitrina
Chasnyk, Vyacheslav
Sengler, Claudia
Klein-Gitelman, Maria
Djeddi, Djamal
Nuno, Laura
Pruunsild, Chris
Brunner, Jurgen
Kondi, Anuela
Pagava, Karaman
Pederzoli, Silvia
Martini, Alberto
Ruperto, Nicolino
PRINTO
Hacettepe Univ
IRCCS G Gaslini
PRINTO
Aarhus Univ Hosp
Rambam Med Ctr
Clin Pediat 1
Istanbul Univ
Meir Med Ctr
Univ Cattolica Sacro Cuore
Med Clin & Sci Immunol Ist
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Hosp Ninos Benjamin Bloom
Hosp Dr Exequiel Gonzalez Cortes
Hop Femme Mere Enfant
Safra Childrens Hosp
Inst Salud Nino
Univ Naples 2
IRCCS Ist G Gaslini
Latvian State Univ
Hosp Univ Pedro Ernesto
Univ Zagreb
Univ G dAnnunzio
King Faisal Specialist Hosp & Res Ctr
Univ Children Hosp
Hosp Paediat Dept
Charite
Childrens Mem Hosp
Dept Pediat
Hosp Gen Univ La Paz
Tartu Univ Hosp
Med Univ
Tblisi State Med Univ
Univ Genoa
Issue Date: 1-May-2010
Publisher: B M J Publishing Group
Citation: Annals of the Rheumatic Diseases. London: B M J Publishing Group, v. 69, n. 5, p. 798-806, 2010.
Abstract: Objectives To validate the previously proposed classification criteria for Henoch-Schonlein purpura (HSP), childhood polyarteritis nodosa (c-PAN), c-Wegener granulomatosis (c-WG) and c-Takayasu arteritis (c-TA).Methods Step 1: retrospective/prospective webdata collection for children with HSP, c-PAN, c-WG and c-TA with age at diagnosis <= 18 years. Step 2: blinded classification by consensus panel of a representative sample of 280 cases. Step 3: statistical (sensitivity, specificity, area under the curve and.-agreement) and nominal group technique consensus evaluations.Results 827 patients with HSP, 150 with c-PAN, 60 with c-WG, 87 with c-TA and 52 with c-other were compared with each other. A patient was classified as HSP in the presence of purpura or petechiae (mandatory) with lower limb predominance plus one of four criteria: (1) abdominal pain; (2) histopathology (IgA); (3) arthritis or arthralgia; (4) renal involvement. Classification of c-PAN required a systemic inflammatory disease with evidence of necrotising vasculitis OR angiographic abnormalities of medium-/small-sized arteries (mandatory criterion) plus one of five criteria: (1) skin involvement; (2) myalgia/muscle tenderness; (3) hypertension; (4) peripheral neuropathy; (5) renal involvement. Classification of c-WG required three of six criteria: (1) histopathological evidence of granulomatous inflammation; (2) upper airway involvement; (3) laryngo-tracheo-bronchial involvement; (4) pulmonary involvement (x-ray/CT); (5) antineutrophilic cytoplasmic antibody positivity; (6) renal involvement. Classification of c-TA required typical angiographic abnormalities of the aorta or its main branches and pulmonary arteries (mandatory criterion) plus one of five criteria: (1) pulse deficit or claudication; (2) blood pressure discrepancy in any limb; (3) bruits; (4) hypertension; (5) elevated acute phase reactant.Conclusion European League Against Rheumatism/Paediatric Rheumatology International Trials Organisation/Paediatric Rheumatology European Society propose validated classification criteria for HSP, c-PAN, c-WG and c-TA with high sensitivity/specificity.
URI: http://repositorio.unifesp.br/handle/11600/32490
ISSN: 0003-4967
Other Identifiers: http://dx.doi.org/10.1136/ard.2009.116657
Appears in Collections:Em verificação - Geral

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