Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/32409
Title: Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae)
Authors: Grecco, Simone S. [UNIFESP]
Reimao, Juliana Q.
Tempone, Andre G.
Sartorelli, Patricia [UNIFESP]
Romoff, Paulete
Ferreira, Marcelo J. P.
Favero, Oriana A.
Lago, Joao H. G. [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Inst Adolfo Lutz Registro
Univ Presbiteriana Mackenzie
Issue Date: 1-Apr-2010
Publisher: Springer
Citation: Parasitology Research. New York: Springer, v. 106, n. 5, p. 1245-1248, 2010.
Abstract: In the course of selection of new bioactive compounds from Brazilian flora, the crude MeOH extract from the leaves of Baccharis retusa DC. (Asteraceae) showed potential against Leishmania sp. and Trypanosoma cruzi. Chromatographic fractionation of the dichloromethane phase from MeOH extract yielded great amounts of the bioactive derivative, which was characterized as 5,6,7-trihydroxy-4'-methoxyflavanone. the structure of this compound was established on the basis of spectroscopic data analysis, mainly nuclear magnetic resonance and mass spectrometry.
URI: http://repositorio.unifesp.br/handle/11600/32409
ISSN: 0932-0113
Other Identifiers: http://dx.doi.org/10.1007/s00436-010-1771-8
Appears in Collections:Em verificação - Geral

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