Please use this identifier to cite or link to this item:
|Title:||The impact of tonic immobility reaction on the prognosis of posttraumatic stress disorder|
|Authors:||Lima, Alessandra A.|
Mendlowicz, Mauro V.
Coutinho, Evandro S. F.
Maia, Deborah C. B.
Mari, Jair J. [UNIFESP]
Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal Fluminense (UFF)
Universidade Federal de São Paulo (UNIFESP)
|Citation:||Journal of Psychiatric Research. Oxford: Pergamon-Elsevier B.V., v. 44, n. 4, p. 224-228, 2010.|
|Abstract:||Tonic immobility is the last defense reaction to entrapment by a predator. in humans, peritraumatic tonic immobility was correlated with PTSD severity and poor response to treatment. This study compared the role of peritraumatic dissociation, panic physical symptoms and tonic immobility as predictors of response to standard pharmacotherapy for PTSD. Thirty-six PTSD patients underwent a naturalistic pharmacological treatment. the Posttraumatic Stress Disorder Checklist - Civilian Version (PCL-C) and the Clinical Global Impressions Severity of Illness item scores (CGI-S) were employed at baseline and endpoint to examine treatment outcome. Peritraumatic reactions were assessed using the Physical Reactions Subscale, the Peritraumatic Dissociative Experiences Questionnaire and four motor questions of the Tonic Immobility Scale. After controlling for confounders, tonic immobility was the best predictor of a poor response to treatment, either considering the PCL-C or the CGI-S scores. Tonic immobility seems to have a greater negative impact on PTSD prognosis than peritraumatic panic or dissociation. Additional translational and clinical research may inform about particular mechanisms underlying tonic immobility and open new avenues for prevention and treatment of PTSD. (C) 2009 Elsevier B.V. All rights reserved.|
|Appears in Collections:||Em verificação - Geral|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.