Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/31934
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dc.contributor.authorScorza, Fulvio A. [UNIFESP]
dc.contributor.authorCysneiros, Roberta M.
dc.contributor.authorTerra, Vera C.
dc.contributor.authorArida, Ricardo M. [UNIFESP]
dc.contributor.authorScorza, Carla A. [UNIFESP]
dc.contributor.authorCavalheiro, Esper A. [UNIFESP]
dc.date.accessioned2016-01-24T13:58:54Z-
dc.date.available2016-01-24T13:58:54Z-
dc.date.issued2009-11-01
dc.identifierhttp://dx.doi.org/10.1016/j.yebeh.2009.09.009
dc.identifier.citationEpilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 16, n. 3, p. 388-390, 2009.
dc.identifier.issn1525-5050
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/31934-
dc.description.abstractIn 1991, a mummy frozen in ice was found by climbers in the Tyrolean Alps. Otzi the Iceman has since been studied in the light of evolutionary explanations for diseases. This year, which marks Charles Darwin's 200th birthday and the 150th anniversary of his publication On the Origin of Species, should re-ignite discussion of the importance of the correlation between nutritional diet and diseases. Epilepsy is one of the commonest diseases in the world. Individuals with epilepsy are at higher risk of death than the general population, and Sudden unexpected death (SUDEP) is the most important direct epilepsy-related Cause of death. A number of factors may influence the risk for SUDEP. Along these lines, several studies have demonstrated that polyunsaturated (omega-3) fatty acids may reduce the risk of cardiovascular mortality, and diminish neuronal excitability. Also, omega-3 fatty acids may decrease seizure frequency, contributing to the reduction of SUDEP risk. Reconstruction of the nutritional patterns of Stone Age humans and optimal human nutrition in the present may be relevant to the prevention and treatment of chromic diseases such as epilepsy and the catastrophic evolution into epilepsy refractoriness and SUDEP. (C) 2009 Elsevier Inc. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent388-390
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofEpilepsy & Behavior
dc.rightsAcesso restrito
dc.subjectDarwinen
dc.subjectEpilepsyen
dc.subjectNutritionen
dc.subjectOmega-3 fatty acidsen
dc.subjectSudden unexplained death in epilepsyen
dc.titleFrom Galapagos to the labs: Darwinian medicine and epilepsy todayen
dc.typeResenha
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Presbiteriana Mackenzie
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Fisiol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Neurol Expt, São Paulo, Brazil
dc.description.affiliationUniv Presbiteriana Mackenzie, Programa Posgrad Disturbios Desenvolvimento, Ctr Ciencias Biol & Saude, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Fac Med Ribeirao Preto, Ctr Cirurgia Epilepsia, Dept Neurociencias & Ciencias Comportamento, Ribeirao Preto, SP, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Fisiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Neurol Expt, São Paulo, Brazil
dc.identifier.doi10.1016/j.yebeh.2009.09.009
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000271935800003
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